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Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype.
Bjursell M, Porritt MJ, Ericson E, Taheri-Ghahfarokhi A, Clausen M, Magnusson L, Admyre T, Nitsch R, Mayr L, Aasehaug L, Seeliger F, Maresca M, Bohlooly-Y M, Wiseman J. Bjursell M, et al. Among authors: ericson e. EBioMedicine. 2018 Mar;29:104-111. doi: 10.1016/j.ebiom.2018.02.015. Epub 2018 Feb 19. EBioMedicine. 2018. PMID: 29500128 Free PMC article.
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model.
Carreras A, Pane LS, Nitsch R, Madeyski-Bengtson K, Porritt M, Akcakaya P, Taheri-Ghahfarokhi A, Ericson E, Bjursell M, Perez-Alcazar M, Seeliger F, Althage M, Knöll R, Hicks R, Mayr LM, Perkins R, Lindén D, Borén J, Bohlooly-Y M, Maresca M. Carreras A, et al. Among authors: ericson e. BMC Biol. 2019 Jan 15;17(1):4. doi: 10.1186/s12915-018-0624-2. BMC Biol. 2019. PMID: 30646909 Free PMC article.
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.
Bestas B, Wimberger S, Degtev D, Madsen A, Rottner AK, Karlsson F, Naumenko S, Callahan M, Touza JL, Francescatto M, Möller CI, Badertscher L, Li S, Cerboni S, Selfjord N, Ericson E, Gordon E, Firth M, Chylinski K, Taheri-Ghahfarokhi A, Bohlooly-Y M, Snowden M, Pangalos M, Nuttall B, Akcakaya P, Sienski G, Maresca M. Bestas B, et al. Among authors: ericson e. Nat Commun. 2023 Sep 6;14(1):5474. doi: 10.1038/s41467-023-41240-7. Nat Commun. 2023. PMID: 37673883 Free PMC article.
Hepatic patatin-like phospholipase domain-containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans.
Ericson E, Bergenholm L, Andréasson AC, Dix CI, Knöchel J, Hansson SF, Lee R, Schumi J, Antonsson M, Fjellström O, Nasr P, Liljeblad M, Carlsson B, Kechagias S, Lindén D, Ekstedt M. Ericson E, et al. Hepatol Commun. 2022 Oct;6(10):2689-2701. doi: 10.1002/hep4.2032. Epub 2022 Jul 14. Hepatol Commun. 2022. PMID: 35833455 Free PMC article.
Phenotypic Screen for Cardiac Regeneration Identifies Molecules with Differential Activity in Human Epicardium-Derived Cells versus Cardiac Fibroblasts.
Paunovic AI, Drowley L, Nordqvist A, Ericson E, Mouchet E, Jonebring A, Grönberg G, Kvist AJ, Engkvist O, Brown MR, Gedda K, Goumans MJ, Wang QD, Plowright AT. Paunovic AI, et al. Among authors: ericson e. ACS Chem Biol. 2017 Jan 20;12(1):132-141. doi: 10.1021/acschembio.6b00683. Epub 2016 Nov 30. ACS Chem Biol. 2017. PMID: 28103692
A novel role of the checkpoint kinase ATR in leptin signaling.
Ericson E, Wennberg Huldt C, Strömstedt M, Brodin P. Ericson E, et al. Mol Cell Endocrinol. 2015 Sep 5;412:257-64. doi: 10.1016/j.mce.2015.04.034. Epub 2015 May 14. Mol Cell Endocrinol. 2015. PMID: 25980679 Free article.
70 results