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Structural Characterization of N-Linked Glycans in the Receptor Binding Domain of the SARS-CoV-2 Spike Protein and their Interactions with Human Lectins.
Lenza MP, Oyenarte I, Diercks T, Quintana JI, Gimeno A, Coelho H, Diniz A, Peccati F, Delgado S, Bosch A, Valle M, Millet O, Abrescia NGA, Palazón A, Marcelo F, Jiménez-Osés G, Jiménez-Barbero J, Ardá A, Ereño-Orbea J. Lenza MP, et al. Angew Chem Int Ed Engl. 2020 Dec 21;59(52):23763-23771. doi: 10.1002/anie.202011015. Epub 2020 Oct 22. Angew Chem Int Ed Engl. 2020. PMID: 32915505 Free PMC article.
Assessing the Mobility of Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Glycans by Structural and Computational Methods.
Stagnoli S, Peccati F, Connell SR, Martinez-Castillo A, Charro D, Millet O, Bruzzone C, Palazon A, Ardá A, Jiménez-Barbero J, Ereño-Orbea J, Abrescia NGA, Jiménez-Osés G. Stagnoli S, et al. Among authors: ereno orbea j. Front Microbiol. 2022 Apr 15;13:870938. doi: 10.3389/fmicb.2022.870938. eCollection 2022. Front Microbiol. 2022. PMID: 35495643 Free PMC article.
Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate.
Prieto-Fernández E, Egia-Mendikute L, Vila-Vecilla L, Bosch A, Barreira-Manrique A, Lee SY, García-Del Río A, Antoñana-Vildosola A, Jiménez-Lasheras B, Moreno-Cugnon L, Jiménez-Barbero J, Berra E, Ereño-Orbea J, Palazon A. Prieto-Fernández E, et al. Emerg Microbes Infect. 2021 Dec;10(1):1065-1076. doi: 10.1080/22221751.2021.1932607. Emerg Microbes Infect. 2021. PMID: 34013835 Free PMC article.
The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes.
Mercado-Gómez M, Prieto-Fernández E, Goikoetxea-Usandizaga N, Vila-Vecilla L, Azkargorta M, Bravo M, Serrano-Maciá M, Egia-Mendikute L, Rodríguez-Agudo R, Lachiondo-Ortega S, Lee SY, Eguileor Giné A, Gil-Pitarch C, González-Recio I, Simón J, Petrov P, Jover R, Martínez-Cruz LA, Ereño-Orbea J, Delgado TC, Elortza F, Jiménez-Barbero J, Nogueiras R, Prevot V, Palazon A, Martínez-Chantar ML. Mercado-Gómez M, et al. Among authors: ereno orbea j. Commun Biol. 2022 Aug 17;5(1):827. doi: 10.1038/s42003-022-03789-9. Commun Biol. 2022. PMID: 35978143 Free PMC article.
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b.
Lenza MP, Egia-Mendikute L, Antoñana-Vildosola A, Soares CO, Coelho H, Corzana F, Bosch A, Manisha P, Quintana JI, Oyenarte I, Unione L, Moure MJ, Azkargorta M, Atxabal U, Sobczak K, Elortza F, Sutherland JD, Barrio R, Marcelo F, Jiménez-Barbero J, Palazon A, Ereño-Orbea J. Lenza MP, et al. Among authors: ereno orbea j. Nat Commun. 2023 Jun 13;14(1):3496. doi: 10.1038/s41467-023-39119-8. Nat Commun. 2023. PMID: 37311743 Free PMC article.
Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody.
Lenza MP, Atxabal U, Nycholat C, Oyenarte I, Franconetti A, Quintana JI, Delgado S, Núñez-Franco R, Garnica Marroquín CT, Coelho H, Unione L, Jiménez-Oses G, Marcelo F, Schubert M, Paulson JC, Jiménez-Barbero J, Ereño-Orbea J. Lenza MP, et al. Among authors: ereno orbea j. JACS Au. 2022 Dec 23;3(1):204-215. doi: 10.1021/jacsau.2c00592. eCollection 2023 Jan 23. JACS Au. 2022. PMID: 36711084 Free PMC article.
30 results