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Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis.
Taha-Mehlitz S, Bianco G, Coto-Llerena M, Kancherla V, Bantug GR, Gallon J, Ercan C, Panebianco F, Eppenberger-Castori S, von Strauss M, Staubli S, Bolli M, Peterli R, Matter MS, Terracciano LM, von Flüe M, Ng CKY, Soysal SD, Kollmar O, Piscuoglio S. Taha-Mehlitz S, et al. Theranostics. 2021 Feb 15;11(9):4011-4029. doi: 10.7150/thno.50051. eCollection 2021. Theranostics. 2021. PMID: 33754045 Free PMC article.
High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favorable prognostic factor.
Droeser RA, Hirt C, Eppenberger-Castori S, Zlobec I, Viehl CT, Frey DM, Nebiker CA, Rosso R, Zuber M, Amicarella F, Iezzi G, Sconocchia G, Heberer M, Lugli A, Tornillo L, Oertli D, Terracciano L, Spagnoli GC. Droeser RA, et al. PLoS One. 2013 May 29;8(5):e64814. doi: 10.1371/journal.pone.0064814. Print 2013. PLoS One. 2013. PMID: 23734221 Free PMC article.
HLA class II antigen expression in colorectal carcinoma tumors as a favorable prognostic marker.
Sconocchia G, Eppenberger-Castori S, Zlobec I, Karamitopoulou E, Arriga R, Coppola A, Caratelli S, Spagnoli GC, Lauro D, Lugli A, Han J, Iezzi G, Ferrone C, Ferlosio A, Tornillo L, Droeser R, Rossi P, Attanasio A, Ferrone S, Terracciano L. Sconocchia G, et al. Neoplasia. 2014 Jan;16(1):31-42. doi: 10.1593/neo.131568. Neoplasia. 2014. PMID: 24563618 Free PMC article.
GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer.
Nebiker CA, Han J, Eppenberger-Castori S, Iezzi G, Hirt C, Amicarella F, Cremonesi E, Huber X, Padovan E, Angrisani B, Droeser RA, Rosso R, Bolli M, Oertli D, von Holzen U, Adamina M, Muraro MG, Mengus C, Zajac P, Sconocchia G, Zuber M, Tornillo L, Terracciano L, Spagnoli GC. Nebiker CA, et al. Clin Cancer Res. 2014 Jun 15;20(12):3094-106. doi: 10.1158/1078-0432.CCR-13-2774. Epub 2014 Apr 15. Clin Cancer Res. 2014. PMID: 24737547
High frequency of CD8 positive lymphocyte infiltration correlates with lack of lymph node involvement in early rectal cancer.
Däster S, Eppenberger-Castori S, Hirt C, Zlobec I, Delko T, Nebiker CA, Soysal SD, Amicarella F, Iezzi G, Sconocchia G, Heberer M, Lugli A, Spagnoli GC, Kettelhack C, Terracciano L, Oertli D, von Holzen U, Tornillo L, Droeser RA. Däster S, et al. Dis Markers. 2014;2014:792183. doi: 10.1155/2014/792183. Epub 2014 Dec 30. Dis Markers. 2014. PMID: 25609852 Free PMC article.
Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed "in vivo".
Hirt C, Papadimitropoulos A, Muraro MG, Mele V, Panopoulos E, Cremonesi E, Ivanek R, Schultz-Thater E, Droeser RA, Mengus C, Heberer M, Oertli D, Iezzi G, Zajac P, Eppenberger-Castori S, Tornillo L, Terracciano L, Martin I, Spagnoli GC. Hirt C, et al. Biomaterials. 2015 Sep;62:138-46. doi: 10.1016/j.biomaterials.2015.05.037. Epub 2015 May 20. Biomaterials. 2015. PMID: 26051518
OX40 expression enhances the prognostic significance of CD8 positive lymphocyte infiltration in colorectal cancer.
Weixler B, Cremonesi E, Sorge R, Muraro MG, Delko T, Nebiker CA, Däster S, Governa V, Amicarella F, Soysal SD, Kettelhack C, von Holzen UW, Eppenberger-Castori S, Spagnoli GC, Oertli D, Iezzi G, Terracciano L, Tornillo L, Sconocchia G, Droeser RA. Weixler B, et al. Oncotarget. 2015 Nov 10;6(35):37588-99. doi: 10.18632/oncotarget.5940. Oncotarget. 2015. PMID: 26439988 Free PMC article.
86 results