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Baeyer-Villiger Monooxygenase-Mediated Synthesis of Esomeprazole As an Alternative for Kagan Sulfoxidation.
Bong YK, Song S, Nazor J, Vogel M, Widegren M, Smith D, Collier SJ, Wilson R, Palanivel SM, Narayanaswamy K, Mijts B, Clay MD, Fong R, Colbeck J, Appaswami A, Muley S, Zhu J, Zhang X, Liang J, Entwistle D. Bong YK, et al. Among authors: entwistle d. J Org Chem. 2018 Jul 20;83(14):7453-7458. doi: 10.1021/acs.joc.8b00468. Epub 2018 Jun 22. J Org Chem. 2018. PMID: 29932340
Inhalation by design: novel tertiary amine muscarinic M₃ receptor antagonists with slow off-rate binding kinetics for inhaled once-daily treatment of chronic obstructive pulmonary disease.
Glossop PA, Watson CA, Price DA, Bunnage ME, Middleton DS, Wood A, James K, Roberts D, Strang RS, Yeadon M, Perros-Huguet C, Clarke NP, Trevethick MA, Machin I, Stuart EF, Evans SM, Harrison AC, Fairman DA, Agoram B, Burrows JL, Feeder N, Fulton CK, Dillon BR, Entwistle DA, Spence FJ. Glossop PA, et al. Among authors: entwistle da. J Med Chem. 2011 Oct 13;54(19):6888-904. doi: 10.1021/jm200884j. Epub 2011 Sep 20. J Med Chem. 2011. PMID: 21870878 Clinical Trial.
Inhalation by design: dual pharmacology β-2 agonists/M3 antagonists for the treatment of COPD.
Jones LH, Baldock H, Bunnage ME, Burrows J, Clarke N, Coghlan M, Entwistle D, Fairman D, Feeder N, Fulton C, Hilton L, James K, Jones RM, Kenyon AS, Marshall S, Newman SD, Osborne R, Patel S, Selby MD, Stuart EF, Trevethick MA, Wright KN, Price DA. Jones LH, et al. Among authors: entwistle d. Bioorg Med Chem Lett. 2011 May 1;21(9):2759-63. doi: 10.1016/j.bmcl.2010.10.132. Epub 2010 Oct 31. Bioorg Med Chem Lett. 2011. PMID: 21075627
An alkyne hydroacylation route to highly substituted furans.
Lenden P, Entwistle DA, Willis MC. Lenden P, et al. Among authors: entwistle da. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10657-60. doi: 10.1002/anie.201105795. Epub 2011 Sep 20. Angew Chem Int Ed Engl. 2011. PMID: 21932241 No abstract available.
A Call to Action.
Duval J, Entwistle D. Duval J, et al. Among authors: entwistle d. J Grad Med Educ. 2018 Aug;10(4):475-476. doi: 10.4300/JGME-D-18-00421.1. J Grad Med Educ. 2018. PMID: 30154987 Free PMC article. No abstract available.
Value Driven Outcomes (VDO): a pragmatic, modular, and extensible software framework for understanding and improving health care costs and outcomes.
Kawamoto K, Martin CJ, Williams K, Tu MC, Park CG, Hunter C, Staes CJ, Bray BE, Deshmukh VG, Holbrook RA, Morris SJ, Fedderson MB, Sletta A, Turnbull J, Mulvihill SJ, Crabtree GL, Entwistle DE, McKenna QL, Strong MB, Pendleton RC, Lee VS. Kawamoto K, et al. Among authors: entwistle de. J Am Med Inform Assoc. 2015 Jan;22(1):223-35. doi: 10.1136/amiajnl-2013-002511. Epub 2014 Oct 16. J Am Med Inform Assoc. 2015. PMID: 25324556 Free PMC article.
18 results