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New non-symmetrical choline kinase inhibitors.
Schiaffino-Ortega S, López-Cara LC, Ríos-Marco P, Carrasco-Jimenez MP, Gallo MA, Espinosa A, Marco C, Entrena A. Schiaffino-Ortega S, et al. Among authors: entrena a. Bioorg Med Chem. 2013 Nov 15;21(22):7146-54. doi: 10.1016/j.bmc.2013.09.003. Epub 2013 Sep 11. Bioorg Med Chem. 2013. PMID: 24080101
Kynurenamines as neural nitric oxide synthase inhibitors.
Entrena A, Camacho ME, Carrión MD, López-Cara LC, Velasco G, León J, Escames G, Acuña-Castroviejo D, Tapias V, Gallo MA, Vivó A, Espinosa A. Entrena A, et al. J Med Chem. 2005 Dec 29;48(26):8174-81. doi: 10.1021/jm050740o. J Med Chem. 2005. PMID: 16366599
Synthesis and biological evaluation of 4,5-dihydro-1H-pyrazole derivatives as potential nNOS/iNOS selective inhibitors. Part 2: Influence of diverse substituents in both the phenyl moiety and the acyl group.
Carrión MD, Chayah M, Entrena A, López A, Gallo MA, Acuña-Castroviejo D, Camacho ME. Carrión MD, et al. Among authors: entrena a. Bioorg Med Chem. 2013 Jul 15;21(14):4132-42. doi: 10.1016/j.bmc.2013.05.016. Epub 2013 May 17. Bioorg Med Chem. 2013. PMID: 23735830
Discovery of a new binding site on human choline kinase α1: design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives.
Rubio-Ruiz B, Figuerola-Conchas A, Ramos-Torrecillas J, Capitán-Cañadas F, Ríos-Marco P, Carrasco MP, Gallo MÁ, Espinosa A, Marco C, Ruiz C, Entrena A, Hurtado-Guerrero R, Conejo-García A. Rubio-Ruiz B, et al. Among authors: entrena a. J Med Chem. 2014 Jan 23;57(2):507-15. doi: 10.1021/jm401665x. Epub 2014 Jan 14. J Med Chem. 2014. PMID: 24387243
Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1).
Schiaffino-Ortega S, Baglioni E, Mariotto E, Bortolozzi R, Serrán-Aguilera L, Ríos-Marco P, Carrasco-Jimenez MP, Gallo MA, Hurtado-Guerrero R, Marco C, Basso G, Viola G, Entrena A, López-Cara LC. Schiaffino-Ortega S, et al. Among authors: entrena a. Sci Rep. 2016 Mar 31;6:23793. doi: 10.1038/srep23793. Sci Rep. 2016. PMID: 27029499 Free PMC article.
51 results