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Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity.
Dos Santos JC, Moreno M, Teufel LU, Chilibroste S, Keating ST, Groh L, Domínguez-Andrés J, Williams DL, Ma Z, Lowman DW, Ensley HE, Novakovic B, Ribeiro-Dias F, Netea MG, Chabalgoity JA, Joosten LAB. Dos Santos JC, et al. Among authors: ensley he. Cell Rep. 2024 Mar 26;43(3):113932. doi: 10.1016/j.celrep.2024.113932. Epub 2024 Mar 7. Cell Rep. 2024. PMID: 38457336 Free PMC article.
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.
Borriello F, Poli V, Shrock E, Spreafico R, Liu X, Pishesha N, Carpenet C, Chou J, Di Gioia M, McGrath ME, Dillen CA, Barrett NA, Lacanfora L, Franco ME, Marongiu L, Iwakura Y, Pucci F, Kruppa MD, Ma Z, Lowman DW, Ensley HE, Nanishi E, Saito Y, O'Meara TR, Seo HS, Dhe-Paganon S, Dowling DJ, Frieman M, Elledge SJ, Levy O, Irvine DJ, Ploegh HL, Williams DL, Zanoni I. Borriello F, et al. Among authors: ensley he. Cell. 2022 Feb 17;185(4):614-629.e21. doi: 10.1016/j.cell.2022.01.009. Epub 2022 Feb 10. Cell. 2022. PMID: 35148840 Free PMC article.
Novel structural features in Candida albicans hyphal glucan provide a basis for differential innate immune recognition of hyphae versus yeast.
Lowman DW, Greene RR, Bearden DW, Kruppa MD, Pottier M, Monteiro MA, Soldatov DV, Ensley HE, Cheng SC, Netea MG, Williams DL. Lowman DW, et al. Among authors: ensley he. J Biol Chem. 2014 Feb 7;289(6):3432-43. doi: 10.1074/jbc.M113.529131. Epub 2013 Dec 16. J Biol Chem. 2014. PMID: 24344127 Free PMC article. Clinical Trial.
Differential high-affinity interaction of dectin-1 with natural or synthetic glucans is dependent upon primary structure and is influenced by polymer chain length and side-chain branching.
Adams EL, Rice PJ, Graves B, Ensley HE, Yu H, Brown GD, Gordon S, Monteiro MA, Papp-Szabo E, Lowman DW, Power TD, Wempe MF, Williams DL. Adams EL, et al. Among authors: ensley he. J Pharmacol Exp Ther. 2008 Apr;325(1):115-23. doi: 10.1124/jpet.107.133124. Epub 2008 Jan 2. J Pharmacol Exp Ther. 2008. PMID: 18171906 Free article.
32 results