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Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion.
Lai PS, Fresco JM, Pinilla MA, Macias AA, Brown RD, Englert JA, Hofmann O, Lederer JA, Hide W, Christiani DC, Cernadas M, Baron RM. Lai PS, et al. Among authors: englert ja. Am J Respir Cell Mol Biol. 2012 Aug;47(2):209-17. doi: 10.1165/rcmb.2011-0447OC. Epub 2012 Apr 19. Am J Respir Cell Mol Biol. 2012. PMID: 22517795 Free PMC article.
A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS.
Fredenburgh LE, Perrella MA, Barragan-Bradford D, Hess DR, Peters E, Welty-Wolf KE, Kraft BD, Harris RS, Maurer R, Nakahira K, Oromendia C, Davies JD, Higuera A, Schiffer KT, Englert JA, Dieffenbach PB, Berlin DA, Lagambina S, Bouthot M, Sullivan AI, Nuccio PF, Kone MT, Malik MJ, Porras MAP, Finkelsztein E, Winkler T, Hurwitz S, Serhan CN, Piantadosi CA, Baron RM, Thompson BT, Choi AM. Fredenburgh LE, et al. Among authors: englert ja. JCI Insight. 2018 Dec 6;3(23):e124039. doi: 10.1172/jci.insight.124039. JCI Insight. 2018. PMID: 30518685 Free PMC article. Clinical Trial.
The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro.
Sappington PL, Cruz RJ Jr, Harada T, Yang R, Han Y, Englert JA, Ajami AA, Killeen ME, Delude RL, Fink MP. Sappington PL, et al. Among authors: englert ja. Biochem Pharmacol. 2005 Nov 25;70(11):1579-92. doi: 10.1016/j.bcp.2005.08.015. Epub 2005 Oct 13. Biochem Pharmacol. 2005. PMID: 16226725
Early High-Dose Vitamin D3 for Critically Ill, Vitamin D-Deficient Patients.
National Heart, Lung, and Blood Institute PETAL Clinical Trials Network; Ginde AA, Brower RG, Caterino JM, Finck L, Banner-Goodspeed VM, Grissom CK, Hayden D, Hough CL, Hyzy RC, Khan A, Levitt JE, Park PK, Ringwood N, Rivers EP, Self WH, Shapiro NI, Thompson BT, Yealy DM, Talmor D. National Heart, Lung, and Blood Institute PETAL Clinical Trials Network, et al. N Engl J Med. 2019 Dec 26;381(26):2529-2540. doi: 10.1056/NEJMoa1911124. Epub 2019 Dec 11. N Engl J Med. 2019. PMID: 31826336 Free PMC article. Clinical Trial.
69 results