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Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells.
Haas AR, Golden RJ, Litzky LA, Engels B, Zhao L, Xu F, Taraszka JA, Ramones M, Granda B, Chang WJ, Jadlowsky J, Shea KM, Runkle A, Chew A, Dowd E, Gonzalez V, Chen F, Liu X, Fang C, Jiang S, Davis MM, Sheppard NC, Zhao Y, Fraietta JA, Lacey SF, Plesa G, Melenhorst JJ, Mansfield K, Brogdon JL, Young RM, Albelda SM, June CH, Tanyi JL. Haas AR, et al. Among authors: engels b. Mol Ther. 2023 Aug 2;31(8):2309-2325. doi: 10.1016/j.ymthe.2023.06.006. Epub 2023 Jun 12. Mol Ther. 2023. PMID: 37312454
A Novel Autologous CAR-T Therapy, YTB323, with Preserved T-cell Stemness Shows Enhanced CAR T-cell Efficacy in Preclinical and Early Clinical Development.
Dickinson MJ, Barba P, Jäger U, Shah NN, Blaise D, Briones J, Shune L, Boissel N, Bondanza A, Mariconti L, Marchal AL, Quinn DS, Yang J, Price A, Sohoni A, Treanor LM, Orlando EJ, Mataraza J, Davis J, Lu D, Zhu X, Engels B, Moutouh-de Parseval L, Brogdon JL, Moschetta M, Flinn IW. Dickinson MJ, et al. Among authors: engels b. Cancer Discov. 2023 Sep 6;13(9):1982-1997. doi: 10.1158/2159-8290.CD-22-1276. Cancer Discov. 2023. PMID: 37249512 Free PMC article.
CAR'TCR-T cells co-expressing CD33-CAR and dNPM1-TCR as superior dual-targeting approach for AML treatment.
Teppert K, Yonezawa Ogusuku IE, Brandes C, Herbel V, Winter N, Werchau N, Khorkova S, Wöhle C, Jelveh N, Bisdorf K, Engels B, Schaser T, Anders K, Künkele A, Lock D. Teppert K, et al. Among authors: engels b. Mol Ther Oncol. 2024 Mar 22;32(2):200797. doi: 10.1016/j.omton.2024.200797. eCollection 2024 Jun 20. Mol Ther Oncol. 2024. PMID: 38601972 Free PMC article.
Synthesis and Reactivity of a Dialane-Bridged Diradical.
Dhara D, Endres L, Krummenacher I, Arrowsmith M, Dewhurst RD, Engels B, Bertermann R, Finze M, Demeshko S, Meyer F, Fantuzzi F, Braunschweig H. Dhara D, et al. Among authors: engels b. Angew Chem Int Ed Engl. 2024 Apr 24;63(18):e202401052. doi: 10.1002/anie.202401052. Epub 2024 Mar 18. Angew Chem Int Ed Engl. 2024. PMID: 38415886
Optical Absorption Properties in Pentacene/Tetracene Solid Solutions.
Unger F, Lepple D, Asbach M, Craciunescu L, Zeiser C, Kandolf AF, Fišer Z, Hagara J, Hagenlocher J, Hiller S, Haug S, Deutsch M, Grüninger P, Novák J, Bettinger HF, Broch K, Engels B, Schreiber F. Unger F, et al. Among authors: engels b. J Phys Chem A. 2024 Feb 1;128(4):747-760. doi: 10.1021/acs.jpca.3c06737. Epub 2024 Jan 17. J Phys Chem A. 2024. PMID: 38232326
306 results