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Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα.
Hanan EJ, Braun MG, Heald RA, MacLeod C, Chan C, Clausen S, Edgar KA, Eigenbrot C, Elliott R, Endres N, Friedman LS, Gogol E, Gu XH, Thibodeau RH, Jackson PS, Kiefer JR, Knight JD, Nannini M, Narukulla R, Pace A, Pang J, Purkey HE, Salphati L, Sampath D, Schmidt S, Sideris S, Song K, Sujatha-Bhaskar S, Ultsch M, Wallweber H, Xin J, Yeap S, Young A, Zhong Y, Staben ST. Hanan EJ, et al. Among authors: endres n. J Med Chem. 2022 Dec 22;65(24):16589-16621. doi: 10.1021/acs.jmedchem.2c01422. Epub 2022 Dec 1. J Med Chem. 2022. PMID: 36455032
Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors.
Nilewski C, Labadie S, Wei B, Malhotra S, Do S, Gazzard L, Liu L, Shao C, Murray J, Izrayelit Y, Gustafson A, Endres NF, Ma F, Ye X, Zou J, Evangelista M. Nilewski C, et al. Among authors: endres nf. ACS Med Chem Lett. 2023 Dec 6;15(1):21-28. doi: 10.1021/acsmedchemlett.3c00478. eCollection 2024 Jan 11. ACS Med Chem Lett. 2023. PMID: 38229748 Free PMC article.
[Comparative study of innate immune gene landscape in bat cells].
Aicher SM, Chantharath A, Kornobis E, Endres N, Tran QD, Diaz IN, Da Fonseca JP, Müller M, Banerjee A, Jouvenet N. Aicher SM, et al. Among authors: endres n. Virologie (Montrouge). 2023 Jun 1;27(3):206-207. doi: 10.1684/vir.2023.1005. Virologie (Montrouge). 2023. PMID: 37462938 French. No abstract available.
Hello darkness, my old friend: 3-KETOACYL-COENZYME A SYNTHASE4 is a branch point in the regulation of triacylglycerol synthesis in Arabidopsis thaliana.
Luzarowska U, Ruß AK, Joubès J, Batsale M, Szymański J, P Thirumalaikumar V, Luzarowski M, Wu S, Zhu F, Endres N, Khedhayir S, Schumacher J, Jasinska W, Xu K, Correa Cordoba SM, Weil S, Skirycz A, Fernie AR, Li-Beisson Y, Fusari CM, Brotman Y. Luzarowska U, et al. Among authors: endres n. Plant Cell. 2023 May 29;35(6):1984-2005. doi: 10.1093/plcell/koad059. Plant Cell. 2023. PMID: 36869652 Free PMC article.
IFN-λ is protective against lethal oral Toxoplasma gondii infection.
Murillo-León M, Bastidas-Quintero AM, Endres NS, Schnepf D, Delgado-Betancourt E, Ohnemus A, Taylor GA, Schwemmle M, Staeheli P, Steinfeldt T. Murillo-León M, et al. Among authors: endres ns. bioRxiv [Preprint]. 2023 Feb 24:2023.02.24.529861. doi: 10.1101/2023.02.24.529861. bioRxiv. 2023. PMID: 36865100 Free PMC article. Preprint.
ROP39 is an Irgb10-specific parasite effector that modulates acute Toxoplasma gondii virulence.
Singh S, Murillo-León M, Endres NS, Arenas Soto AF, Gómez-Marín JE, Melbert F, Kanneganti TD, Yamamoto M, Campos C, Howard JC, Taylor GA, Steinfeldt T. Singh S, et al. Among authors: endres ns. PLoS Pathog. 2023 Jan 5;19(1):e1011003. doi: 10.1371/journal.ppat.1011003. eCollection 2023 Jan. PLoS Pathog. 2023. PMID: 36603017 Free PMC article.
Repair of Quadriceps and Patellar Tendon Tears.
Danaher M, Faucett SC, Endres NK, Geeslin AG. Danaher M, et al. Among authors: endres nk. Arthroscopy. 2023 Feb;39(2):142-144. doi: 10.1016/j.arthro.2022.10.034. Epub 2022 Nov 2. Arthroscopy. 2023. PMID: 36332853
The Duration of Thigh Tourniquet Use Associated With Anterior Cruciate Ligament Reconstruction Does Not Produce Cellular-Level Contractile Dysfunction of the Quadriceps Muscle at 3 Weeks After Surgery.
Beynnon BD, Pius AK, Tourville TW, Endres NK, Failla MJ, Choquette RH, DeSarno M, Toth MJ. Beynnon BD, et al. Among authors: endres nk. Am J Sports Med. 2022 Sep;50(11):2925-2934. doi: 10.1177/03635465221115823. Epub 2022 Aug 18. Am J Sports Med. 2022. PMID: 35980007
49 results