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Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity.
Gnad T, Navarro G, Lahesmaa M, Reverte-Salisa L, Copperi F, Cordomi A, Naumann J, Hochhäuser A, Haufs-Brusberg S, Wenzel D, Suhr F, Jespersen NZ, Scheele C, Tsvilovskyy V, Brinkmann C, Rittweger J, Dani C, Kranz M, Deuther-Conrad W, Eltzschig HK, Niemi T, Taittonen M, Brust P, Nuutila P, Pardo L, Fleischmann BK, Blüher M, Franco R, Bloch W, Virtanen KA, Pfeifer A. Gnad T, et al. Among authors: eltzschig hk. Cell Metab. 2022 Apr 5;34(4):649. doi: 10.1016/j.cmet.2022.02.014. Cell Metab. 2022. PMID: 35385706 Free article. No abstract available.
Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity.
Gnad T, Navarro G, Lahesmaa M, Reverte-Salisa L, Copperi F, Cordomi A, Naumann J, Hochhäuser A, Haufs-Brusberg S, Wenzel D, Suhr F, Jespersen NZ, Scheele C, Tsvilovskyy V, Brinkmann C, Rittweger J, Dani C, Kranz M, Deuther-Conrad W, Eltzschig HK, Niemi T, Taittonen M, Brust P, Nuutila P, Pardo L, Fleischmann BK, Blüher M, Franco R, Bloch W, Virtanen KA, Pfeifer A. Gnad T, et al. Among authors: eltzschig hk. Cell Metab. 2020 Jul 7;32(1):56-70.e7. doi: 10.1016/j.cmet.2020.06.006. Epub 2020 Jun 25. Cell Metab. 2020. PMID: 32589947 Free PMC article.
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.
Niemann B, Haufs-Brusberg S, Puetz L, Feickert M, Jaeckstein MY, Hoffmann A, Zurkovic J, Heine M, Trautmann EM, Müller CE, Tönjes A, Schlein C, Jafari A, Eltzschig HK, Gnad T, Blüher M, Krahmer N, Kovacs P, Heeren J, Pfeifer A. Niemann B, et al. Among authors: eltzschig hk. Nature. 2022 Sep;609(7926):361-368. doi: 10.1038/s41586-022-05041-0. Epub 2022 Jul 5. Nature. 2022. PMID: 35790189 Free PMC article.
Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.
Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, Sun K, Glover L, Grenz A, Sun H, Tao L, Zhang W, Colgan SP, Blackburn MR, Eltzschig HK, Kellems RE, Xia Y. Zhang W, et al. Among authors: eltzschig hk. Circ Res. 2013 May 24;112(11):1466-78. doi: 10.1161/CIRCRESAHA.111.300166. Epub 2013 Apr 12. Circ Res. 2013. PMID: 23584256 Free PMC article.
The resurgence of A2B adenosine receptor signaling.
Aherne CM, Kewley EM, Eltzschig HK. Aherne CM, et al. Among authors: eltzschig hk. Biochim Biophys Acta. 2011 May;1808(5):1329-39. doi: 10.1016/j.bbamem.2010.05.016. Epub 2010 May 28. Biochim Biophys Acta. 2011. PMID: 20546702 Free PMC article. Review.
Detrimental effects of adenosine signaling in sickle cell disease.
Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia Y. Zhang Y, et al. Among authors: eltzschig hk. Nat Med. 2011 Jan;17(1):79-86. doi: 10.1038/nm.2280. Epub 2010 Dec 19. Nat Med. 2011. PMID: 21170046 Free PMC article.
CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy.
Tak E, Ridyard D, Kim JH, Zimmerman M, Werner T, Wang XX, Shabeka U, Seo SW, Christians U, Klawitter J, Moldovan R, Garcia G, Levi M, Haase V, Ravid K, Eltzschig HK, Grenz A. Tak E, et al. Among authors: eltzschig hk. J Am Soc Nephrol. 2014 Mar;25(3):547-63. doi: 10.1681/ASN.2012101014. Epub 2013 Nov 21. J Am Soc Nephrol. 2014. PMID: 24262796 Free PMC article.
Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells.
El-Naccache DW, Chen F, Palma MJ, Lemenze A, Fischer MA, Wu W, Mishra PK, Eltzschig HK, Robson SC, Di Virgilio F, Yap GS, Edelblum KL, Haskó G, Gause WC. El-Naccache DW, et al. Among authors: eltzschig hk. Cell Rep. 2022 Aug 2;40(5):111150. doi: 10.1016/j.celrep.2022.111150. Cell Rep. 2022. PMID: 35926464 Free PMC article.
314 results