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Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders.
Zhao S, Lin Q, Xiong W, Li L, Straub L, Zhang D, Zapata R, Zhu Q, Sun XN, Zhang Z, Funcke JB, Li C, Chen S, Zhu Y, Jiang N, Li G, Xu Z, Wyler SC, Wang MY, Bai J, Han X, Kusminski CM, Zhang N, An Z, Elmquist JK, Osborn O, Liu C, Scherer PE. Zhao S, et al. Among authors: elmquist jk. Sci Transl Med. 2023 Nov 22;15(723):eade8460. doi: 10.1126/scitranslmed.ade8460. Epub 2023 Nov 22. Sci Transl Med. 2023. PMID: 37992151
Leptin Reduction as a Required Component for Weight Loss.
Zhao S, Li N, Xiong W, Li G, He S, Zhang Z, Zhu Q, Jiang N, Ikejiofor C, Zhu Y, Wang MY, Han X, Zhang N, Solis-Herrera C, Kusminski C, An Z, Elmquist JK, Scherer PE. Zhao S, et al. Among authors: elmquist jk. Diabetes. 2024 Feb 1;73(2):197-210. doi: 10.2337/db23-0571. Diabetes. 2024. PMID: 37935033
Neuronal E93 is required for adaptation to adult metabolism and behavior.
Yip C, Wyler SC, Liang K, Yamazaki S, Cobb T, Safdar M, Metai A, Merchant W, Wessells R, Rothenfluh A, Lee S, Elmquist J, You YJ. Yip C, et al. Mol Metab. 2024 Apr 16;84:101939. doi: 10.1016/j.molmet.2024.101939. Online ahead of print. Mol Metab. 2024. PMID: 38621602 Free PMC article.
Obesity: an evolutionary context.
Speakman JR, Elmquist JK. Speakman JR, et al. Among authors: elmquist jk. Life Metab. 2022 Apr 29;1(1):10-24. doi: 10.1093/lifemeta/loac002. eCollection 2022 Aug. Life Metab. 2022. PMID: 36394061 Free PMC article. Review.
An enteroendocrine-microbial axis in the large intestine controls host metabolism.
Tan S, Santolaya J, Wright TF, Liu Q, Fujikawa T, Chi S, Bergstrom CP, Lopez A, Chen Q, do Vale GD, McDonald JG, Jia D, Elmquist JK, Sifuentes-Dominguez L, Burstein E. Tan S, et al. Among authors: elmquist jk. Res Sq [Preprint]. 2023 Jul 6:rs.3.rs-3112286. doi: 10.21203/rs.3.rs-3112286/v1. Res Sq. 2023. PMID: 37461519 Free PMC article. Preprint.
Hepatic non-parenchymal S100A9-TLR4-mTORC1 axis normalizes diabetic ketogenesis.
Ursino G, Ramadori G, Höfler A, Odouard S, Teixeira PDS, Visentin F, Veyrat-Durebex C, Lucibello G, Firnkes R, Ricci S, Vianna CR, Jia L, Dirlewanger M, Klee P, Elmquist JK, Roth J, Vogl T, Schwitzgebel VM, Jornayvaz FR, Boland A, Coppari R. Ursino G, et al. Among authors: elmquist jk. Nat Commun. 2022 Jul 15;13(1):4107. doi: 10.1038/s41467-022-31803-5. Nat Commun. 2022. PMID: 35840613 Free PMC article.
Response to Kunos et al. and Lotersztajn and Mallat.
Wang S, Zhu Q, Liang G, Franks T, Boucher M, Bence KK, Lu M, Castorena CM, Zhao S, Elmquist JK, Scherer PE, Horton JD. Wang S, et al. Among authors: elmquist jk. J Clin Invest. 2022 Jan 4;132(1):e156247. doi: 10.1172/JCI156247. J Clin Invest. 2022. PMID: 34981782 Free PMC article. No abstract available.
CB1Rs in VMH neurons regulate glucose homeostasis but not body weight.
Castorena CM, Caron A, Michael NJ, Ahmed NI, Arnold AG, Lee J, Lee C, Limboy C, Tinajero AS, Granier M, Wang S, Horton JD, Holland WL, Lee S, Liu C, Fujikawa T, Elmquist JK. Castorena CM, et al. Among authors: elmquist jk. Am J Physiol Endocrinol Metab. 2021 Jul 1;321(1):E146-E155. doi: 10.1152/ajpendo.00044.2021. Epub 2021 Jun 7. Am J Physiol Endocrinol Metab. 2021. PMID: 34097543 Free PMC article.
220 results