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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 1
2004 2
2006 1
2007 1
2008 2
2009 1
2010 1
2011 3
2013 2
2014 5
2015 9
2016 7
2017 8
2018 11
2019 12
2020 8
2021 13
2022 7
2023 8
2024 2

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94 results

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Page 1
Lactoylglutathione promotes inflammatory signaling in macrophages through histone lactoylation.
Trujillo MN, Jennings EQ, Hoffman EA, Zhang H, Phoebe AM, Mastin GE, Kitamura N, Reisz JA, Megill E, Kantner D, Marcinkiewicz MM, Twardy SM, Lebario F, Chapman E, McCullough RL, D'Alessandro A, Snyder NW, Cusanovich DA, Galligan JJ. Trujillo MN, et al. Among authors: chapman e. Mol Metab. 2024 Mar;81:101888. doi: 10.1016/j.molmet.2024.101888. Epub 2024 Feb 1. Mol Metab. 2024. PMID: 38307385 Free PMC article.
Human Hsp70 Substrate-Binding Domains Recognize Distinct Client Proteins.
Ambrose AJ, Zerio CJ, Sivinski J, Zhu X, Godek J, Sanchez JL, Khanna M, Khanna R, Lairson L, Zhang DD, Chapman E. Ambrose AJ, et al. Among authors: chapman e. Biochemistry. 2024 Feb 6;63(3):251-263. doi: 10.1021/acs.biochem.3c00531. Epub 2024 Jan 20. Biochemistry. 2024. PMID: 38243804
Lactoylglutathione promotes inflammatory signaling in macrophages.
Trujillo MN, Jennings EQ, Hoffman EA, Zhang H, Phoebe AM, Mastin GE, Kitamura N, Reisz JA, Megill E, Kantner D, Marcinkiewicz MM, Twardy SM, Lebario F, Chapman E, McCullough RL, D'Alessandro A, Snyder NW, Cusanovich DA, Galligan JJ. Trujillo MN, et al. Among authors: chapman e. bioRxiv [Preprint]. 2023 Oct 10:2023.10.10.561739. doi: 10.1101/2023.10.10.561739. bioRxiv. 2023. PMID: 37873172 Free PMC article. Updated. Preprint.
The NRF2-p97-NRF2 negative feedback loop.
Shakya A, Liu P, Godek J, McKee NW, Dodson M, Anandhan A, Ooi A, Garcia JGN, Costa M, Chapman E, Zhang DD. Shakya A, et al. Among authors: chapman e. Redox Biol. 2023 Sep;65:102839. doi: 10.1016/j.redox.2023.102839. Epub 2023 Aug 9. Redox Biol. 2023. PMID: 37573837 Free PMC article.
Anti-Ferroptotic Effects of Nrf2: Beyond the Antioxidant Response.
Shakya A, McKee NW, Dodson M, Chapman E, Zhang DD. Shakya A, et al. Among authors: chapman e. Mol Cells. 2023 Mar 31;46(3):165-175. doi: 10.14348/molcells.2023.0005. Epub 2023 Mar 24. Mol Cells. 2023. PMID: 36994475 Free PMC article. Review.
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8.
Anandhan A, Dodson M, Shakya A, Chen J, Liu P, Wei Y, Tan H, Wang Q, Jiang Z, Yang K, Garcia JG, Chambers SK, Chapman E, Ooi A, Yang-Hartwich Y, Stockwell BR, Zhang DD. Anandhan A, et al. Among authors: chapman e. Sci Adv. 2023 Feb 3;9(5):eade9585. doi: 10.1126/sciadv.ade9585. Epub 2023 Feb 1. Sci Adv. 2023. PMID: 36724221 Free PMC article.
Physachenolide C is a Potent, Selective BET Inhibitor.
Zerio CJ, Sivinski J, Wijeratne EMK, Xu YM, Ngo DT, Ambrose AJ, Villa-Celis L, Ghadirian N, Clarkson MW, Zhang DD, Horton NC, Gunatilaka AAL, Fromme R, Chapman E. Zerio CJ, et al. Among authors: chapman e. J Med Chem. 2023 Jan 12;66(1):913-933. doi: 10.1021/acs.jmedchem.2c01770. Epub 2022 Dec 28. J Med Chem. 2023. PMID: 36577036
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78.
Ambrose AJ, Sivinski J, Zerio CJ, Zhu X, Godek J, Kumirov VK, Coma Brujas T, Torra Garcia J, Annadurai A, Schmidlin CJ, Werner A, Shi T, Zavareh RB, Lairson L, Zhang DD, Chapman E. Ambrose AJ, et al. Among authors: chapman e. J Med Chem. 2023 Jan 12;66(1):677-694. doi: 10.1021/acs.jmedchem.2c01631. Epub 2022 Dec 14. J Med Chem. 2023. PMID: 36516003
Bis-aryl-α,β-unsaturated ketone (ABK) chaperonin inhibitors exhibit selective cytotoxicity to colorectal cancer cells that correlates with levels of aberrant HSP60 in the cytosol.
Chitre S, Ray AM, Stevens M, Doud EH, Liechty H, Washburn A, Tepper K, Sivinski J, O'Hagan HM, Georgiadis MM, Chapman E, Johnson SM. Chitre S, et al. Among authors: chapman e. Bioorg Med Chem. 2022 Dec 1;75:117072. doi: 10.1016/j.bmc.2022.117072. Epub 2022 Oct 30. Bioorg Med Chem. 2022. PMID: 36356534
94 results