Elgaher WAM - Search Results

1

A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria.

Richter R, Kamal MAM, García-Rivera MA, Kaspar J, Junk M, Elgaher WAM, Srikakulam SK, Gress A, Beckmann A, Grißmer A, Meier C, Vielhaber M, Kalinina O, Hirsch AKH, Hartmann RW, Brönstrup M, Schneider-Daum N, Lehr CM. Richter R, et al. Among authors: elgaher wam. Mater Today Bio. 2020 Nov 2;8:100084. doi: 10.1016/j.mtbio.2020.100084. eCollection 2020 Sep. Mater Today Bio. 2020. PMID: 33313504 Free PMC article.

2

Surface plasmon resonance--more than a screening technology: insights in the binding mode of σ70:core RNAP inhibitors.

Hüsecken K, Hinsberger S, Elgaher WA, Haupenthal J, Hartmann RW. Hüsecken K, et al. Future Med Chem. 2014 Sep;6(14):1551-65. doi: 10.4155/fmc.14.105. Future Med Chem. 2014. PMID: 25367390

3

Discovery and Structure-Based Optimization of 2-Ureidothiophene-3-carboxylic Acids as Dual Bacterial RNA Polymerase and Viral Reverse Transcriptase Inhibitors.

Elgaher WA, Sharma KK, Haupenthal J, Saladini F, Pires M, Real E, Mély Y, Hartmann RW. Elgaher WA, et al. J Med Chem. 2016 Aug 11;59(15):7212-22. doi: 10.1021/acs.jmedchem.6b00730. Epub 2016 Jul 7. J Med Chem. 2016. PMID: 27339173

4

In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics.

Graef F, Richter R, Fetz V, Murgia X, De Rossi C, Schneider-Daum N, Allegretta G, Elgaher W, Haupenthal J, Empting M, Beckmann F, Brönstrup M, Hartmann R, Gordon S, Lehr CM. Graef F, et al. ACS Infect Dis. 2018 Aug 10;4(8):1188-1196. doi: 10.1021/acsinfecdis.7b00165. Epub 2018 May 24. ACS Infect Dis. 2018. PMID: 29750862

5

Reversible immobilization of a protein to a gold surface through multiple host-guest interactions.

Schwarz DH, Elgaher WAM, Hollemeyer K, Hirsch AKH, Wenz G. Schwarz DH, et al. Among authors: elgaher wam. J Mater Chem B. 2019 Oct 16;7(40):6148-6155. doi: 10.1039/c9tb00560a. J Mater Chem B. 2019. PMID: 31555792

6

Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis.

Lababidi N, Ofosu Kissi E, Elgaher WAM, Sigal V, Haupenthal J, Schwarz BC, Hirsch AKH, Rades T, Schneider M. Lababidi N, et al. Among authors: elgaher wam. J Control Release. 2019 Nov 28;314:62-71. doi: 10.1016/j.jconrel.2019.10.038. Epub 2019 Oct 22. J Control Release. 2019. PMID: 31654686

7

Semisynthesis and biological evaluation of amidochelocardin derivatives as broad-spectrum antibiotics.

Grandclaudon C, Birudukota NVS, Elgaher WAM, Jumde RP, Yahiaoui S, Arisetti N, Hennessen F, Hüttel S, Stadler M, Herrmann J, Miethke M, Hartmann RW, Müller R, Hirsch AKH, Brönstrup M. Grandclaudon C, et al. Among authors: elgaher wam. Eur J Med Chem. 2020 Feb 15;188:112005. doi: 10.1016/j.ejmech.2019.112005. Epub 2019 Dec 20. Eur J Med Chem. 2020. PMID: 31911294

8

Cystobactamid 507: Concise Synthesis, Mode of Action, and Optimization toward More Potent Antibiotics.

Elgaher WAM, Hamed MM, Baumann S, Herrmann J, Siebenbürger L, Krull J, Cirnski K, Kirschning A, Brönstrup M, Müller R, Hartmann RW. Elgaher WAM, et al. Chemistry. 2020 Jun 5;26(32):7219-7225. doi: 10.1002/chem.202000117. Epub 2020 Apr 28. Chemistry. 2020. PMID: 31984562 Free PMC article.

9

Protein-Templated Hit Identification through an Ugi Four-Component Reaction*.

Mancini F, Unver MY, Elgaher WAM, Jumde VR, Alhayek A, Lukat P, Herrmann J, Witte MD, Köck M, Blankenfeldt W, Müller R, Hirsch AKH. Mancini F, et al. Among authors: elgaher wam. Chemistry. 2020 Nov 17;26(64):14585-14593. doi: 10.1002/chem.202002250. Epub 2020 Sep 30. Chemistry. 2020. PMID: 32428268 Free PMC article.

10

Discovery of Small-Molecule Stabilizers of 14-3-3 Protein-Protein Interactions via Dynamic Combinatorial Chemistry.

Hartman AM, Elgaher WAM, Hertrich N, Andrei SA, Ottmann C, Hirsch AKH. Hartman AM, et al. Among authors: elgaher wam. ACS Med Chem Lett. 2020 Feb 28;11(5):1041-1046. doi: 10.1021/acsmedchemlett.9b00541. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435423 Free PMC article.

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