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2019 3
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2023 2
2024 3

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First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer's Disease.
Santini A, Tassinari E, Poeta E, Loi M, Ciani E, Trazzi S, Piccarducci R, Daniele S, Martini C, Pagliarani B, Tarozzi A, Bersani M, Spyrakis F, Danková D, Olsen CA, Soldati R, Tumiatti V, Montanari S, De Simone A, Milelli A. Santini A, et al. Among authors: poeta e. ACS Chem Neurosci. 2024 May 15. doi: 10.1021/acschemneuro.4c00061. Online ahead of print. ACS Chem Neurosci. 2024. PMID: 38747979
Transcriptional and metabolic effects of aspartate-glutamate carrier isoform 1 (AGC1) downregulation in mouse oligodendrocyte precursor cells (OPCs).
Balboni N, Babini G, Poeta E, Protti M, Mercolini L, Magnifico MC, Barile SN, Massenzio F, Pignataro A, Giorgi FM, Lasorsa FM, Monti B. Balboni N, et al. Among authors: poeta e. Cell Mol Biol Lett. 2024 Mar 29;29(1):44. doi: 10.1186/s11658-024-00563-z. Cell Mol Biol Lett. 2024. PMID: 38553684 Free PMC article.
Targeted quantitative metabolic profiling of brain-derived cell cultures by semi-automated MEPS and LC-MS/MS.
Protti M, Cirrincione M, Palano S, Poeta E, Babini G, Magnifico MC, Barile SN, Balboni N, Massenzio F, Mahdavijalal M, Giorgi FM, Mandrioli R, Lasorsa FM, Monti B, Mercolini L. Protti M, et al. Among authors: poeta e. J Pharm Biomed Anal. 2023 Nov 30;236:115757. doi: 10.1016/j.jpba.2023.115757. Epub 2023 Sep 29. J Pharm Biomed Anal. 2023. PMID: 37801818 Free article.
Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer's Disease Mouse Model.
Spatz P, Steinmüller SAM, Tutov A, Poeta E, Morilleau A, Carles A, Deventer MH, Hofmann J, Stove CP, Monti B, Maurice T, Decker M. Spatz P, et al. Among authors: poeta e. J Med Chem. 2023 May 11;66(9):6414-6435. doi: 10.1021/acs.jmedchem.3c00541. Epub 2023 Apr 26. J Med Chem. 2023. PMID: 37127287 Free PMC article.
Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease.
Gandini A, Gonçalves AE, Strocchi S, Albertini C, Janočková J, Tramarin A, Grifoni D, Poeta E, Soukup O, Muñoz-Torrero D, Monti B, Sabaté R, Bartolini M, Legname G, Bolognesi ML. Gandini A, et al. Among authors: poeta e. ACS Chem Neurosci. 2022 Dec 7;13(23):3314-3329. doi: 10.1021/acschemneuro.2c00357. Epub 2022 Nov 29. ACS Chem Neurosci. 2022. PMID: 36445009 Free PMC article.
Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate-Glutamate Carrier Isoform 1 Deficiency.
Poeta E, Petralla S, Babini G, Renzi B, Celauro L, Magnifico MC, Barile SN, Masotti M, De Chirico F, Massenzio F, Viggiano L, Palmieri L, Virgili M, Lasorsa FM, Monti B. Poeta E, et al. Front Cell Neurosci. 2022 Jan 12;15:773709. doi: 10.3389/fncel.2021.773709. eCollection 2021. Front Cell Neurosci. 2022. PMID: 35095421 Free PMC article.
Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer's Disease Mouse Model.
Scheiner M, Hoffmann M, He F, Poeta E, Chatonnet A, Monti B, Maurice T, Decker M. Scheiner M, et al. Among authors: poeta e. J Med Chem. 2021 Jul 8;64(13):9302-9320. doi: 10.1021/acs.jmedchem.1c00534. Epub 2021 Jun 21. J Med Chem. 2021. PMID: 34152756
Melatonin- and Ferulic Acid-Based HDAC6 Selective Inhibitors Exhibit Pronounced Immunomodulatory Effects In Vitro and Neuroprotective Effects in a Pharmacological Alzheimer's Disease Mouse Model.
He F, Chou CJ, Scheiner M, Poeta E, Yuan Chen N, Gunesch S, Hoffmann M, Sotriffer C, Monti B, Maurice T, Decker M. He F, et al. Among authors: poeta e. J Med Chem. 2021 Apr 8;64(7):3794-3812. doi: 10.1021/acs.jmedchem.0c01940. Epub 2021 Mar 26. J Med Chem. 2021. PMID: 33769811
14 results