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456 results

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Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.
Wainwright CE, Elborn JS, Ramsey BW, Marigowda G, Huang X, Cipolli M, Colombo C, Davies JC, De Boeck K, Flume PA, Konstan MW, McColley SA, McCoy K, McKone EF, Munck A, Ratjen F, Rowe SM, Waltz D, Boyle MP; TRAFFIC Study Group; TRANSPORT Study Group. Wainwright CE, et al. Among authors: elborn js. N Engl J Med. 2015 Jul 16;373(3):220-31. doi: 10.1056/NEJMoa1409547. Epub 2015 May 17. N Engl J Med. 2015. PMID: 25981758 Free PMC article. Clinical Trial.
Multicenter randomized controlled trial of withdrawal of inhaled corticosteroids in cystic fibrosis.
Balfour-Lynn IM, Lees B, Hall P, Phillips G, Khan M, Flather M, Elborn JS; CF WISE (Withdrawal of Inhaled Steroids Evaluation) Investigators. Balfour-Lynn IM, et al. Among authors: elborn js. Am J Respir Crit Care Med. 2006 Jun 15;173(12):1356-62. doi: 10.1164/rccm.200511-1808OC. Epub 2006 Mar 23. Am J Respir Crit Care Med. 2006. PMID: 16556691 Clinical Trial.
Ancestral haplotype 8.1 and lung disease severity in European cystic fibrosis patients.
Corvol H, Beucher J, Boëlle PY, Busson PF, Muselet-Charlier C, Clement A, Ratjen F, Grasemann H, Laki J, Palmer CN, Elborn JS, Mehta A. Corvol H, et al. Among authors: elborn js. J Cyst Fibros. 2012 Jan;11(1):63-7. doi: 10.1016/j.jcf.2011.09.006. Epub 2011 Oct 10. J Cyst Fibros. 2012. PMID: 21993476 Free article.
A CFTR potentiator in patients with cystic fibrosis and the G551D mutation.
Ramsey BW, Davies J, McElvaney NG, Tullis E, Bell SC, Dřevínek P, Griese M, McKone EF, Wainwright CE, Konstan MW, Moss R, Ratjen F, Sermet-Gaudelus I, Rowe SM, Dong Q, Rodriguez S, Yen K, Ordoñez C, Elborn JS; VX08-770-102 Study Group. Ramsey BW, et al. Among authors: elborn js. N Engl J Med. 2011 Nov 3;365(18):1663-72. doi: 10.1056/NEJMoa1105185. N Engl J Med. 2011. PMID: 22047557 Free PMC article. Clinical Trial.
Antibiotic and anti-inflammatory therapies for cystic fibrosis.
Chmiel JF, Konstan MW, Elborn JS. Chmiel JF, et al. Among authors: elborn js. Cold Spring Harb Perspect Med. 2013 Oct 1;3(10):a009779. doi: 10.1101/cshperspect.a009779. Cold Spring Harb Perspect Med. 2013. PMID: 23880054 Free PMC article. Review.
BIIL 284 reduces neutrophil numbers but increases P. aeruginosa bacteremia and inflammation in mouse lungs.
Döring G, Bragonzi A, Paroni M, Aktürk FF, Cigana C, Schmidt A, Gilpin D, Heyder S, Born T, Smaczny C, Kohlhäufl M, Wagner TO, Loebinger MR, Bilton D, Tunney MM, Elborn JS, Pier GB, Konstan MW, Ulrich M. Döring G, et al. Among authors: elborn js. J Cyst Fibros. 2014 Mar;13(2):156-63. doi: 10.1016/j.jcf.2013.10.007. Epub 2013 Oct 31. J Cyst Fibros. 2014. PMID: 24183915 Free PMC article.
Assessment of clinical response to ivacaftor with lung clearance index in cystic fibrosis patients with a G551D-CFTR mutation and preserved spirometry: a randomised controlled trial.
Davies J, Sheridan H, Bell N, Cunningham S, Davis SD, Elborn JS, Milla CE, Starner TD, Weiner DJ, Lee PS, Ratjen F. Davies J, et al. Among authors: elborn js. Lancet Respir Med. 2013 Oct;1(8):630-638. doi: 10.1016/S2213-2600(13)70182-6. Epub 2013 Sep 10. Lancet Respir Med. 2013. PMID: 24461666 Clinical Trial.
Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial.
Kerem E, Konstan MW, De Boeck K, Accurso FJ, Sermet-Gaudelus I, Wilschanski M, Elborn JS, Melotti P, Bronsveld I, Fajac I, Malfroot A, Rosenbluth DB, Walker PA, McColley SA, Knoop C, Quattrucci S, Rietschel E, Zeitlin PL, Barth J, Elfring GL, Welch EM, Branstrom A, Spiegel RJ, Peltz SW, Ajayi T, Rowe SM; Cystic Fibrosis Ataluren Study Group. Kerem E, et al. Among authors: elborn js. Lancet Respir Med. 2014 Jul;2(7):539-47. doi: 10.1016/S2213-2600(14)70100-6. Epub 2014 May 15. Lancet Respir Med. 2014. PMID: 24836205 Free PMC article. Clinical Trial.
Antibiotic management of lung infections in cystic fibrosis. I. The microbiome, methicillin-resistant Staphylococcus aureus, gram-negative bacteria, and multiple infections.
Chmiel JF, Aksamit TR, Chotirmall SH, Dasenbrook EC, Elborn JS, LiPuma JJ, Ranganathan SC, Waters VJ, Ratjen FA. Chmiel JF, et al. Among authors: elborn js. Ann Am Thorac Soc. 2014 Sep;11(7):1120-9. doi: 10.1513/AnnalsATS.201402-050AS. Ann Am Thorac Soc. 2014. PMID: 25102221 Free PMC article. Review.
456 results