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Discovery of 2,4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms.
Eldehna WM, Taghour MS, Al-Warhi T, Nocentini A, Elbadawi MM, Mahdy HA, Abdelrahman MA, Alotaibi OJ, Aljaeed N, Elimam DM, Afarinkia K, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Among authors: elbadawi mm. J Enzyme Inhib Med Chem. 2022 Dec;37(1):531-541. doi: 10.1080/14756366.2021.2024528. J Enzyme Inhib Med Chem. 2022. PMID: 34991416 Free PMC article.
Identification of N-phenyl-2-(phenylsulfonyl)acetamides/propanamides as new SLC-0111 analogues: Synthesis and evaluation of the carbonic anhydrase inhibitory activities.
Elbadawi MM, Eldehna WM, Nocentini A, Abo-Ashour MF, Elkaeed EB, Abdelgawad MA, Alharbi KS, Abdel-Aziz HA, Supuran CT, Gratteri P, Al-Sanea MM. Elbadawi MM, et al. Eur J Med Chem. 2021 Jun 5;218:113360. doi: 10.1016/j.ejmech.2021.113360. Epub 2021 Mar 13. Eur J Med Chem. 2021. PMID: 33773285
Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII.
Al-Warhi T, Elbadawi MM, Bonardi A, Nocentini A, Al-Karmalawy AA, Aljaeed N, Alotaibi OJ, Abdel-Aziz HA, Supuran CT, Eldehna WM. Al-Warhi T, et al. Among authors: elbadawi mm. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2635-2643. doi: 10.1080/14756366.2022.2124409. J Enzyme Inhib Med Chem. 2022. PMID: 36146927 Free PMC article.
Design and synthesis of 6-arylpyridine-tethered sulfonamides as novel selective inhibitors of carbonic anhydrase IX with promising antitumor features toward the human colorectal cancer.
Eldehna WM, Mohammed EE, Al-Ansary GH, Berrino E, Elbadawi MM, Ibrahim TM, Jaballah MY, Al-Rashood ST, Binjubair FA, Celik M, Nocentini A, Elbarbry FA, Sahin F, Abdel-Aziz HA, Supuran CT, Fares M. Eldehna WM, et al. Among authors: elbadawi mm. Eur J Med Chem. 2023 Oct 5;258:115538. doi: 10.1016/j.ejmech.2023.115538. Epub 2023 Jun 1. Eur J Med Chem. 2023. PMID: 37321108
Development of new thiazolidine-2,4-dione hybrids as aldose reductase inhibitors endowed with antihyperglycaemic activity: design, synthesis, biological investigations, and in silico insights.
Hamdi A, Yaseen M, Ewes WA, Bhat MA, Ziedan NI, El-Shafey HW, Mohamed AAB, Elnagar MR, Haikal A, Othman DIA, Elgazar AA, Abusabaa AHA, Abdelrahman KS, Soltan OM, Elbadawi MM. Hamdi A, et al. Among authors: elbadawi mm. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2231170. doi: 10.1080/14756366.2023.2231170. J Enzyme Inhib Med Chem. 2023. PMID: 37470409 Free PMC article.
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