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SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation.
Xu Z, Choi JH, Dai DL, Luo J, Ladak RJ, Li Q, Wang Y, Zhang C, Wiebe S, Liu ACH, Ran X, Yang J, Naeli P, Garzia A, Zhou L, Mahmood N, Deng Q, Elaish M, Lin R, Mahal LK, Hobman TC, Pelletier J, Alain T, Vidal SM, Duchaine T, Mazhab-Jafari MT, Mao X, Jafarnejad SM, Sonenberg N. Xu Z, et al. Among authors: elaish m. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204539119. doi: 10.1073/pnas.2204539119. Epub 2022 Jul 25. Proc Natl Acad Sci U S A. 2022. PMID: 35878012 Free PMC article.
Glycomic analysis of host response reveals high mannose as a key mediator of influenza severity.
Heindel DW, Koppolu S, Zhang Y, Kasper B, Meche L, Vaiana CA, Bissel SJ, Carter CE, Kelvin AA, Elaish M, Lopez-Orozco J, Zhang B, Zhou B, Chou TW, Lashua L, Hobman TC, Ross TM, Ghedin E, Mahal LK. Heindel DW, et al. Among authors: elaish m. Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26926-26935. doi: 10.1073/pnas.2008203117. Epub 2020 Oct 12. Proc Natl Acad Sci U S A. 2020. PMID: 33046650 Free PMC article.
Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.
Nguyen L, McCord KA, Bui DT, Bouwman KM, Kitova EN, Elaish M, Kumawat D, Daskhan GC, Tomris I, Han L, Chopra P, Yang TJ, Willows SD, Mason AL, Mahal LK, Lowary TL, West LJ, Hsu SD, Hobman T, Tompkins SM, Boons GJ, de Vries RP, Macauley MS, Klassen JS. Nguyen L, et al. Among authors: elaish m. Nat Chem Biol. 2022 Jan;18(1):81-90. doi: 10.1038/s41589-021-00924-1. Epub 2021 Nov 9. Nat Chem Biol. 2022. PMID: 34754101
26 results