El-Khamisy SF - Search Results

1

DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat.

Boughey H, Jurga M, El-Khamisy SF. Boughey H, et al. Int J Mol Sci. 2021 Jun 2;22(11):6011. doi: 10.3390/ijms22116011. Int J Mol Sci. 2021. PMID: 34199458 Free PMC article. Review.

2

C9orf72 expansion disrupts ATM-mediated chromosomal break repair.

Walker C, Herranz-Martin S, Karyka E, Liao C, Lewis K, Elsayed W, Lukashchuk V, Chiang SC, Ray S, Mulcahy PJ, Jurga M, Tsagakis I, Iannitti T, Chandran J, Coldicott I, De Vos KJ, Hassan MK, Higginbottom A, Shaw PJ, Hautbergue GM, Azzouz M, El-Khamisy SF. Walker C, et al. Nat Neurosci. 2017 Sep;20(9):1225-1235. doi: 10.1038/nn.4604. Epub 2017 Jul 17. Nat Neurosci. 2017. PMID: 28714954 Free PMC article.

3

DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity.

Kok JR, Palminha NM, Dos Santos Souza C, El-Khamisy SF, Ferraiuolo L. Kok JR, et al. Cell Mol Life Sci. 2021 Aug;78(15):5707-5729. doi: 10.1007/s00018-021-03872-0. Epub 2021 Jun 26. Cell Mol Life Sci. 2021. PMID: 34173837 Free PMC article. Review.

4

USP11 controls R-loops by regulating senataxin proteostasis.

Jurga M, Abugable AA, Goldman ASH, El-Khamisy SF. Jurga M, et al. Nat Commun. 2021 Sep 15;12(1):5156. doi: 10.1038/s41467-021-25459-w. Nat Commun. 2021. PMID: 34526504 Free PMC article.

5

A mechanism for oxidative damage repair at gene regulatory elements.

Ray S, Abugable AA, Parker J, Liversidge K, Palminha NM, Liao C, Acosta-Martin AE, Souza CDS, Jurga M, Sudbery I, El-Khamisy SF. Ray S, et al. Among authors: el khamisy sf. Nature. 2022 Sep;609(7929):1038-1047. doi: 10.1038/s41586-022-05217-8. Epub 2022 Sep 28. Nature. 2022. PMID: 36171374 Free article.

6

Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing.

Carroll J, Page TK, Chiang SC, Kalmar B, Bode D, Greensmith L, Mckinnon PJ, Thorpe JR, Hafezparast M, El-Khamisy SF. Carroll J, et al. Hum Mol Genet. 2015 Feb 1;24(3):828-40. doi: 10.1093/hmg/ddu500. Epub 2014 Sep 30. Hum Mol Genet. 2015. PMID: 25274775 Free PMC article.

7

Role of Protein Linked DNA Breaks in Cancer.

Allam WR, Ashour ME, Waly AA, El-Khamisy S. Allam WR, et al. Adv Exp Med Biol. 2017;1007:41-58. doi: 10.1007/978-3-319-60733-7_3. Adv Exp Med Biol. 2017. PMID: 28840551

8

A role for Rad5 in ribonucleoside monophosphate (rNMP) tolerance.

Elserafy M, El-Shiekh I, Fleifel D, Atteya R, AlOkda A, Abdrabbou MM, Nasr M, El-Khamisy SF. Elserafy M, et al. Life Sci Alliance. 2021 Aug 18;4(10):e202000966. doi: 10.26508/lsa.202000966. Print 2021 Oct. Life Sci Alliance. 2021. PMID: 34407997 Free PMC article.

9

Defective repair of topoisomerase I induced chromosomal damage in Huntington's disease.

Palminha NM, Dos Santos Souza C, Griffin J, Liao C, Ferraiuolo L, El-Khamisy SF. Palminha NM, et al. Cell Mol Life Sci. 2022 Feb 28;79(3):160. doi: 10.1007/s00018-022-04204-6. Cell Mol Life Sci. 2022. PMID: 35224690 Free PMC article.

10

High Glucose Increases DNA Damage and Elevates the Expression of Multiple DDR Genes.

Rahmoon MA, Elghaish RA, Ibrahim AA, Alaswad Z, Gad MZ, El-Khamisy SF, Elserafy M. Rahmoon MA, et al. Among authors: el khamisy sf. Genes (Basel). 2023 Jan 5;14(1):144. doi: 10.3390/genes14010144. Genes (Basel). 2023. PMID: 36672885 Free PMC article.

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