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α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
Fauvet B, Mbefo MK, Fares MB, Desobry C, Michael S, Ardah MT, Tsika E, Coune P, Prudent M, Lion N, Eliezer D, Moore DJ, Schneider B, Aebischer P, El-Agnaf OM, Masliah E, Lashuel HA. Fauvet B, et al. J Biol Chem. 2012 May 4;287(19):15345-64. doi: 10.1074/jbc.M111.318949. Epub 2012 Feb 7. J Biol Chem. 2012. PMID: 22315227 Free PMC article.
Alpha-Synuclein Produces Early Behavioral Alterations via Striatal Cholinergic Synaptic Dysfunction by Interacting With GluN2D N-Methyl-D-Aspartate Receptor Subunit.
Tozzi A, de Iure A, Bagetta V, Tantucci M, Durante V, Quiroga-Varela A, Costa C, Di Filippo M, Ghiglieri V, Latagliata EC, Wegrzynowicz M, Decressac M, Giampà C, Dalley JW, Xia J, Gardoni F, Mellone M, El-Agnaf OM, Ardah MT, Puglisi-Allegra S, Björklund A, Spillantini MG, Picconi B, Calabresi P. Tozzi A, et al. Biol Psychiatry. 2016 Mar 1;79(5):402-414. doi: 10.1016/j.biopsych.2015.08.013. Epub 2015 Aug 20. Biol Psychiatry. 2016. PMID: 26392130
Retraction Notice to: Corrigendum to "Development of Nonviral Vectors Targeting the Brain as a Therapeutic Approach For Parkinson's Disease and Other Brain Disorders".
Javed H, Menon SA, Al-Mansoori KM, Al-Wandi A, Majbour NK, Ardah MT, Varghese S, Vaikath NN, Haque ME, Azzouz M, El-Agnaf OM. Javed H, et al. Among authors: el agnaf om. Mol Ther. 2024 Apr 11:S1525-0016(24)00233-8. doi: 10.1016/j.ymthe.2024.04.016. Online ahead of print. Mol Ther. 2024. PMID: 38608701 No abstract available.
Retraction Notice to: Development of Nonviral Vectors Targeting the Brain as a Therapeutic Approach For Parkinson's Disease and Other Brain Disorders.
Javed H, Menon SA, Al-Mansoori KM, Al-Wandi A, Majbour NK, Ardah MT, Varghese S, Vaikath NN, Haque ME, Azzouz M, El-Agnaf OM. Javed H, et al. Among authors: el agnaf om. Mol Ther. 2024 Apr 11:S1525-0016(24)00232-6. doi: 10.1016/j.ymthe.2024.04.015. Online ahead of print. Mol Ther. 2024. PMID: 38608700 No abstract available.
Untargeted Metabolomic Profiling Reveals Differentially Expressed Serum Metabolites and Pathways in Type 2 Diabetes Patients with and without Cognitive Decline: A Cross-Sectional Study.
Al-Akl NS, Khalifa O, Ponirakis G, Parray A, Ramadan M, Khan S, Chandran M, Ayadathil R, Elsotouhy A, Own A, Al Hamad H, Decock J, Alajez NM, Albagha O, Malik RA, El-Agnaf OMA, Arredouani A. Al-Akl NS, et al. Among authors: el agnaf oma. Int J Mol Sci. 2024 Feb 13;25(4):2247. doi: 10.3390/ijms25042247. Int J Mol Sci. 2024. PMID: 38396924 Free PMC article.
Corrigendum to " Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy Body Disease" [Neurobiology of Disease127 (2019) 163-177].
Spencer B, Trinh I, Rockenstein E, Mante M, Florio J, Adame A, El-Agnaf OMA, Kim C, Masliah E, Rissman RA. Spencer B, et al. Among authors: el agnaf oma. Neurobiol Dis. 2024 Feb;191:106397. doi: 10.1016/j.nbd.2023.106397. Epub 2024 Jan 12. Neurobiol Dis. 2024. PMID: 38216383 Free article. No abstract available.
144 results