Eggink D - Search Results

1

Is there a future for antiviral fusion inhibitors?

Berkhout B, Eggink D, Sanders RW. Berkhout B, et al. Among authors: eggink d. Curr Opin Virol. 2012 Feb;2(1):50-9. doi: 10.1016/j.coviro.2012.01.002. Epub 2012 Jan 28. Curr Opin Virol. 2012. PMID: 22440966 Review.

2

Evolution of a novel 5-amino-acid insertion in the beta3-beta4 loop of HIV-1 reverse transcriptase.

Huigen MC, de Graaf L, Eggink D, Schuurman R, Müller V, Stamp A, Stammers DK, Boucher CA, Nijhuis M. Huigen MC, et al. Among authors: eggink d. Virology. 2007 Aug 1;364(2):395-406. doi: 10.1016/j.virol.2007.03.028. Epub 2007 Apr 23. Virology. 2007. PMID: 17451772 Free article.

3

Antibodies to HIV-1: aiming at the right target.

Eggink D, Melchers M, Sanders RW. Eggink D, et al. Trends Microbiol. 2007 Jul;15(7):291-4. doi: 10.1016/j.tim.2007.05.006. Epub 2007 Jun 12. Trends Microbiol. 2007. PMID: 17566740

4

The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion.

Sanders RW, van Anken E, Nabatov AA, Liscaljet IM, Bontjer I, Eggink D, Melchers M, Busser E, Dankers MM, Groot F, Braakman I, Berkhout B, Paxton WA. Sanders RW, et al. Among authors: eggink d. Retrovirology. 2008 Jan 31;5:10. doi: 10.1186/1742-4690-5-10. Retrovirology. 2008. PMID: 18237398 Free PMC article.

5

Selection of T1249-resistant human immunodeficiency virus type 1 variants.

Eggink D, Baldwin CE, Deng Y, Langedijk JP, Lu M, Sanders RW, Berkhout B. Eggink D, et al. J Virol. 2008 Jul;82(13):6678-88. doi: 10.1128/JVI.00352-08. Epub 2008 Apr 23. J Virol. 2008. PMID: 18434391 Free PMC article.

6

Optimization of human immunodeficiency virus type 1 envelope glycoproteins with V1/V2 deleted, using virus evolution.

Bontjer I, Land A, Eggink D, Verkade E, Tuin K, Baldwin C, Pollakis G, Paxton WA, Braakman I, Berkhout B, Sanders RW. Bontjer I, et al. Among authors: eggink d. J Virol. 2009 Jan;83(1):368-83. doi: 10.1128/JVI.01404-08. Epub 2008 Oct 15. J Virol. 2009. PMID: 18922866 Free PMC article.

7

Detailed mechanistic insights into HIV-1 sensitivity to three generations of fusion inhibitors.

Eggink D, Langedijk JP, Bonvin AM, Deng Y, Lu M, Berkhout B, Sanders RW. Eggink D, et al. J Biol Chem. 2009 Sep 25;284(39):26941-50. doi: 10.1074/jbc.M109.004416. Epub 2009 Jul 17. J Biol Chem. 2009. PMID: 19617355 Free PMC article.

8

Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function.

Eggink D, Melchers M, Wuhrer M, van Montfort T, Dey AK, Naaijkens BA, David KB, Le Douce V, Deelder AM, Kang K, Olson WC, Berkhout B, Hokke CH, Moore JP, Sanders RW. Eggink D, et al. Virology. 2010 Jun 5;401(2):236-47. doi: 10.1016/j.virol.2010.02.019. Epub 2010 Mar 21. Virology. 2010. PMID: 20304457 Free PMC article.

9

Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization.

Binley JM, Ban YE, Crooks ET, Eggink D, Osawa K, Schief WR, Sanders RW. Binley JM, et al. Among authors: eggink d. J Virol. 2010 Jun;84(11):5637-55. doi: 10.1128/JVI.00105-10. Epub 2010 Mar 24. J Virol. 2010. PMID: 20335257 Free PMC article.

10

Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution.

Bontjer I, Melchers M, Eggink D, David K, Moore JP, Berkhout B, Sanders RW. Bontjer I, et al. Among authors: eggink d. J Biol Chem. 2010 Nov 19;285(47):36456-70. doi: 10.1074/jbc.M110.156588. Epub 2010 Sep 8. J Biol Chem. 2010. PMID: 20826824 Free PMC article.

The design of the trimers was guided by HIV-1 evolution studies that identified compensatory changes in V1V2-deleted but functional Env proteins (Bontjer, I., Land, A., Eggink, D., Verkade, E., Tuin, K., Baldwin, C., Pollakis, G., Paxton, W. ...

The design of the trimers was guided by HIV-1 evolution studies that identified compensatory changes in V1V2-deleted but functional Env prot …

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