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The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function.
Vanderhaeghen T, Timmermans S, Eggermont M, Watts D, Vandewalle J, Wallaeys C, Nuyttens L, De Temmerman J, Hochepied T, Dewaele S, Berghe JV, Sanders N, Wielockx B, Beyaert R, Libert C. Vanderhaeghen T, et al. Among authors: eggermont m. Front Immunol. 2023 Mar 16;14:1124011. doi: 10.3389/fimmu.2023.1124011. eCollection 2023. Front Immunol. 2023. PMID: 37006237 Free PMC article.
The Education Pipeline of Biomimetics and Its Challenges.
Jacobs S, Eggermont M, Helms M, Wanieck K. Jacobs S, et al. Among authors: eggermont m. Biomimetics (Basel). 2022 Jul 7;7(3):93. doi: 10.3390/biomimetics7030093. Biomimetics (Basel). 2022. PMID: 35892363 Free PMC article.
Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding.
Timmermans S, Verhoog NJD, Van Looveren K, Dewaele S, Hochepied T, Eggermont M, Gilbert B, Boerema-de Munck A, Vanderhaeghen T, Vanden Berghe J, Garcia Gonzalez N, Vandewalle J, Bloch Y, Provost M, Savvides SN, De Bosscher K, Declercq W, Rottier RJ, Louw A, Libert C. Timmermans S, et al. Among authors: eggermont m. J Biol Chem. 2022 Feb;298(2):101574. doi: 10.1016/j.jbc.2022.101574. Epub 2022 Jan 8. J Biol Chem. 2022. PMID: 35007536 Free PMC article.
Reprogramming of glucocorticoid receptor function by hypoxia.
Vanderhaeghen T, Timmermans S, Watts D, Paakinaho V, Eggermont M, Vandewalle J, Wallaeys C, Van Wyngene L, Van Looveren K, Nuyttens L, Dewaele S, Vanden Berghe J, Lemeire K, De Backer J, Dirkx L, Vanden Berghe W, Caljon G, Ghesquière B, De Bosscher K, Wielockx B, Palvimo JJ, Beyaert R, Libert C. Vanderhaeghen T, et al. Among authors: eggermont m. EMBO Rep. 2022 Jan 5;23(1):e53083. doi: 10.15252/embr.202153083. Epub 2021 Oct 26. EMBO Rep. 2022. PMID: 34699114 Free PMC article.
Triple Therapy for Cystic Fibrosis Phe508del-Gating and -Residual Function Genotypes.
Barry PJ, Mall MA, Álvarez A, Colombo C, de Winter-de Groot KM, Fajac I, McBennett KA, McKone EF, Ramsey BW, Sutharsan S, Taylor-Cousar JL, Tullis E, Ahluwalia N, Jun LS, Moskowitz SM, Prieto-Centurion V, Tian S, Waltz D, Xuan F, Zhang Y, Rowe SM, Polineni D; VX18-445-104 Study Group. Barry PJ, et al. N Engl J Med. 2021 Aug 26;385(9):815-825. doi: 10.1056/NEJMoa2100665. N Engl J Med. 2021. PMID: 34437784 Free PMC article. Clinical Trial.
35 results