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Prediction Model for Antimalarial Activities of Hemozoin Inhibitors by Using Physicochemical Properties.
Mosaddeque F, Mizukami S, Kamel MG, Teklemichael AA, Dat TV, Mizuta S, Toan DV, Ahmed AM, Vuong NL, Elhady MT, Giang HTN, Dang TN, Fukuda M, Huynh LK, Tanaka Y, Egan TJ, Kaneko O, Huy NT, Hirayama K. Mosaddeque F, et al. Among authors: egan tj. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02424-17. doi: 10.1128/AAC.02424-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29439979 Free PMC article.
Quinoline antimalarials containing a dibemethin group are active against chloroquinone-resistant Plasmodium falciparum and inhibit chloroquine transport via the P. falciparum chloroquine-resistance transporter (PfCRT).
Zishiri VK, Joshi MC, Hunter R, Chibale K, Smith PJ, Summers RL, Martin RE, Egan TJ. Zishiri VK, et al. Among authors: egan tj. J Med Chem. 2011 Oct 13;54(19):6956-68. doi: 10.1021/jm2009698. Epub 2011 Sep 13. J Med Chem. 2011. PMID: 21875063
Identification and deconvolution of cross-resistance signals from antimalarial compounds using multidrug-resistant Plasmodium falciparum strains.
Chugh M, Scheurer C, Sax S, Bilsland E, van Schalkwyk DA, Wicht KJ, Hofmann N, Sharma A, Bashyam S, Singh S, Oliver SG, Egan TJ, Malhotra P, Sutherland CJ, Beck HP, Wittlin S, Spangenberg T, Ding XC. Chugh M, et al. Among authors: egan tj. Antimicrob Agents Chemother. 2015 Feb;59(2):1110-8. doi: 10.1128/AAC.03265-14. Epub 2014 Dec 8. Antimicrob Agents Chemother. 2015. PMID: 25487796 Free PMC article.
171 results