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Pharmaco-Toxicological Effects of Atypical Synthetic Cathinone Mephtetramine (MTTA) in Mice: Possible Reasons for Its Brief Appearance over NPSs Scene.
Corli G, Tirri M, Arfè R, Marchetti B, Bernardi T, Borsari M, Odoardi S, Mestria S, Strano-Rossi S, Neri M, Gaudio RM, Bilel S, Marti M. Corli G, et al. Brain Sci. 2023 Jan 18;13(2):161. doi: 10.3390/brainsci13020161. Brain Sci. 2023. PMID: 36831704 Free PMC article.
Among these, synthetic cathinones seem to become increasingly popular among young adults, mainly because of their ability to replicate the effects of traditional psychostimulant drugs, such as cocaine, MDMA and amphetamines. However, scarce data are available about the in …
Among these, synthetic cathinones seem to become increasingly popular among young adults, mainly because of their ability to replicate the …
Human Neuronal Cell Lines as An In Vitro Toxicological Tool for the Evaluation of Novel Psychoactive Substances.
Sogos V, Caria P, Porcedda C, Mostallino R, Piras F, Miliano C, De Luca MA, Castelli MP. Sogos V, et al. Int J Mol Sci. 2021 Jun 24;22(13):6785. doi: 10.3390/ijms22136785. Int J Mol Sci. 2021. PMID: 34202634 Free PMC article.
Novel psychoactive substances (NPS) are synthetic substances belonging to diverse groups, designed to mimic the effects of scheduled drugs, resulting in altered toxicity and potency. Up to now, information available on the pharmacology and toxicology of these …
Novel psychoactive substances (NPS) are synthetic substances belonging to diverse groups, designed to mimic the effects of sch …
Acute DOB and PMA Administration Impairs Motor and Sensorimotor Responses in Mice and Causes Hallucinogenic Effects in Adult Zebrafish.
Tirri M, Ponzoni L, Bilel S, Arfè R, Braida D, Sala M, Marti M. Tirri M, et al. Brain Sci. 2020 Aug 24;10(9):586. doi: 10.3390/brainsci10090586. Brain Sci. 2020. PMID: 32847111 Free PMC article.
In fact, these two substances seem to induce the same effects as MDMA, which could be due to their structural similarities. According to users, DOB and PMA share the same euphoric effects: increasing of the mental state, increasing sociability and empathy. ...
In fact, these two substances seem to induce the same effects as MDMA, which could be due to their structural similarities. According …
Genotoxic Properties of Synthetic Cannabinoids on TK6 Human Cells by Flow Cytometry.
Lenzi M, Cocchi V, Cavazza L, Bilel S, Hrelia P, Marti M. Lenzi M, et al. Int J Mol Sci. 2020 Feb 9;21(3):1150. doi: 10.3390/ijms21031150. Int J Mol Sci. 2020. PMID: 32050487 Free PMC article.
SCBs are more dangerous than delta(9)-Tetrahydrocannabinol as a consequence of their stronger affinities for the CB(1) and CB(2) receptors, which may result in longer duration of distinct effects, greater potency, and toxicity. The information on SCBs cytotoxicity, …
SCBs are more dangerous than delta(9)-Tetrahydrocannabinol as a consequence of their stronger affinities for the CB(1) and CB(2) receptors, …
Acute and repeated administration of MDPV increases aggressive behavior in mice: forensic implications.
De-Giorgio F, Bilel S, Ossato A, Tirri M, Arfè R, Foti F, Serpelloni G, Frisoni P, Neri M, Marti M. De-Giorgio F, et al. Int J Legal Med. 2019 Nov;133(6):1797-1808. doi: 10.1007/s00414-019-02092-3. Epub 2019 Jun 1. Int J Legal Med. 2019. PMID: 31154497
MDPV is a synthetic cathinone illegally marketed and consumed for its psychostimulant effects, which are similar to those produced by cocaine, amphetamines, and MDMA. ...Moreover, the aggressive and locomotor responses are enhanced after repeated administration, ind …
MDPV is a synthetic cathinone illegally marketed and consumed for its psychostimulant effects, which are similar to those produced by …