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In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy.
Nat Commun. 2021 May 24;12(1):3055. doi: 10.1038/s41467-021-23316-4.
Nat Commun. 2021.
PMID: 34031411
Free PMC article.
Role of Grb10 in mTORC1-dependent regulation of insulin signaling and action in human skeletal muscle cells.
Edick AM, Auclair O, Burgos SA.
Edick AM, et al.
Am J Physiol Endocrinol Metab. 2020 Feb 1;318(2):E173-E183. doi: 10.1152/ajpendo.00025.2019. Epub 2019 Dec 3.
Am J Physiol Endocrinol Metab. 2020.
PMID: 31794259
Free article.
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CRISPR-Cas9-mediated knockout of GCN2 reveals a critical role in sensing amino acid deprivation in bovine mammary epithelial cells.
Edick AM, Audette J, Burgos SA.
Edick AM, et al.
J Dairy Sci. 2021 Jan;104(1):1123-1135. doi: 10.3168/jds.2020-18700. Epub 2020 Nov 6.
J Dairy Sci. 2021.
PMID: 33162067
Free article.
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Inhibition of AKT Sensitizes Cancer Cells to Antineoplastic Drugs by Downregulating Flap Endonuclease 1.
Zhu H, Wu C, Wu T, Xia W, Ci S, He W, Zhang Y, Li L, Zhou S, Zhang J, Edick AM, Zhang A, Pan FY, Hu Z, He L, Guo Z.
Zhu H, et al. Among authors: edick am.
Mol Cancer Ther. 2019 Dec;18(12):2407-2420. doi: 10.1158/1535-7163.MCT-18-1215. Epub 2019 Aug 29.
Mol Cancer Ther. 2019.
PMID: 31467180
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Two-way crosstalk between BER and c-NHEJ repair pathway is mediated by Pol-β and Ku70.
Xia W, Ci S, Li M, Wang M, Dianov GL, Ma Z, Li L, Hua K, Alagamuthu KK, Qing L, Luo L, Edick AM, Liu L, Hu Z, He L, Pan F, Guo Z.
Xia W, et al. Among authors: edick am.
FASEB J. 2019 Nov;33(11):11668-11681. doi: 10.1096/fj.201900308R. Epub 2019 Jul 26.
FASEB J. 2019.
PMID: 31348687
Free PMC article.
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Wnt pathway is involved in 5-FU drug resistance of colorectal cancer cells.
He L, Zhu H, Zhou S, Wu T, Wu H, Yang H, Mao H, SekharKathera C, Janardhan A, Edick AM, Zhang A, Hu Z, Pan F, Guo Z.
He L, et al. Among authors: edick am.
Exp Mol Med. 2018 Aug 14;50(8):1-12. doi: 10.1038/s12276-018-0128-8.
Exp Mol Med. 2018.
PMID: 30111797
Free PMC article.
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