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Pig kidney xenotransplantation: Progress toward clinical trials.
Cooper DKC, Hara H, Iwase H, Yamamoto T, Wang ZY, Jagdale A, Bikhet MH, Nguyen HQ, Foote JB, Paris WD, Ayares D, Kumar V, Anderson DJ, Locke JE, Eckhoff DE. Cooper DKC, et al. Among authors: eckhoff de. Clin Transplant. 2021 Jan;35(1):e14139. doi: 10.1111/ctr.14139. Epub 2020 Nov 19. Clin Transplant. 2021. PMID: 33131148 Review.
Life-supporting Kidney Xenotransplantation From Genetically Engineered Pigs in Baboons: A Comparison of Two Immunosuppressive Regimens.
Yamamoto T, Hara H, Foote J, Wang L, Li Q, Klein EC, Schuurman HJ, Zhou H, Li J, Tector AJ, Zhang Z, Ezzelarab M, Lovingood R, Ayares D, Eckhoff DE, Cooper DKC, Iwase H. Yamamoto T, et al. Among authors: eckhoff de. Transplantation. 2019 Oct;103(10):2090-2104. doi: 10.1097/TP.0000000000002796. Transplantation. 2019. PMID: 31283686
Clinical Pig Kidney Xenotransplantation: How Close Are We?
Cooper DKC, Hara H, Iwase H, Yamamoto T, Jagdale A, Kumar V, Mannon RB, Hanaway MJ, Anderson DJ, Eckhoff DE. Cooper DKC, et al. Among authors: eckhoff de. J Am Soc Nephrol. 2020 Jan;31(1):12-21. doi: 10.1681/ASN.2019070651. Epub 2019 Dec 2. J Am Soc Nephrol. 2020. PMID: 31792154 Free PMC article. Review.
The final obstacle to successful pre-clinical xenotransplantation?
Yamamoto T, Hara H, Iwase H, Jagdale A, Bikhet MH, Morsi MA, Cui Y, Nguyen HQ, Wang ZY, Anderson DJ, Foote J, Schuurman HJ, Ayares D, Eckhoff DE, Cooper DKC. Yamamoto T, et al. Among authors: eckhoff de. Xenotransplantation. 2020 Sep;27(5):e12596. doi: 10.1111/xen.12596. Epub 2020 Jun 25. Xenotransplantation. 2020. PMID: 32585053
Evidence suggesting that deletion of expression of N-glycolylneuraminic acid (Neu5Gc) in the organ-source pig is associated with increased antibody-mediated rejection of kidney transplants in baboons.
Iwase H, Jagdale A, Yamamoto T, Bikhet MH, Nguyen HQ, Ezzelarab M, Ayares D, Anderson DJ, Eckhoff DE, Foote JB, Fatima H, Schuurman HJ, Hara H, Cooper DKC. Iwase H, et al. Among authors: eckhoff de. Xenotransplantation. 2021 Jul;28(4):e12700. doi: 10.1111/xen.12700. Epub 2021 May 25. Xenotransplantation. 2021. PMID: 34036638
Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons.
Foote JB, Jagdale A, Yamamoto T, Hara H, Bikhet MH, Schuurman HJ, Nguyen HQ, Ezzelarab M, Ayares D, Anderson DJ, Fatima H, Eckhoff DE, Cooper DKC, Iwase H. Foote JB, et al. Among authors: eckhoff de. Xenotransplantation. 2021 Nov;28(6):e12715. doi: 10.1111/xen.12715. Epub 2021 Oct 13. Xenotransplantation. 2021. PMID: 34644438 Free PMC article.
167 results