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Mitochondrial dysfunction--a pharmacological target in Alzheimer's disease.
Eckert GP, Renner K, Eckert SH, Eckmann J, Hagl S, Abdel-Kader RM, Kurz C, Leuner K, Muller WE. Eckert GP, et al. Among authors: eckert sh. Mol Neurobiol. 2012 Aug;46(1):136-50. doi: 10.1007/s12035-012-8271-z. Epub 2012 May 3. Mol Neurobiol. 2012. PMID: 22552779 Review.
Rice bran extract protects from mitochondrial dysfunction in guinea pig brains.
Hagl S, Kocher A, Schiborr C, Eckert SH, Ciobanu I, Birringer M, El-Askary H, Helal A, Khayyal MT, Frank J, Muller WE, Eckert GP. Hagl S, et al. Among authors: eckert sh. Pharmacol Res. 2013 Oct;76:17-27. doi: 10.1016/j.phrs.2013.06.008. Epub 2013 Jul 1. Pharmacol Res. 2013. PMID: 23827162
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation.
Leuner K, Schütt T, Kurz C, Eckert SH, Schiller C, Occhipinti A, Mai S, Jendrach M, Eckert GP, Kruse SE, Palmiter RD, Brandt U, Dröse S, Wittig I, Willem M, Haass C, Reichert AS, Müller WE. Leuner K, et al. Among authors: eckert gp, eckert sh. Antioxid Redox Signal. 2012 Jun 15;16(12):1421-33. doi: 10.1089/ars.2011.4173. Epub 2012 Feb 28. Antioxid Redox Signal. 2012. PMID: 22229260 Free PMC article.
MH84 improves mitochondrial dysfunction in a mouse model of early Alzheimer's disease.
Pohland M, Pellowska M, Asseburg H, Hagl S, Reutzel M, Joppe A, Berressem D, Eckert SH, Wurglics M, Schubert-Zsilavecz M, Eckert GP. Pohland M, et al. Among authors: eckert sh. Alzheimers Res Ther. 2018 Feb 13;10(1):18. doi: 10.1186/s13195-018-0342-6. Alzheimers Res Ther. 2018. PMID: 29433569 Free PMC article.
13 results