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Nalmefene is effective at reducing alcohol seeking, treating alcohol-cocaine interactions and reducing alcohol-induced histone deacetylases gene expression in blood.
Calleja-Conde J, Echeverry-Alzate V, Giné E, Bühler KM, Nadal R, Maldonado R, Rodríguez de Fonseca F, Gual A, López-Moreno JA. Calleja-Conde J, et al. Br J Pharmacol. 2016 Aug;173(16):2490-505. doi: 10.1111/bph.13526. Epub 2016 Jul 18. Br J Pharmacol. 2016. PMID: 27238566 Free PMC article.
Cocaine reverses the naltrexone-induced reduction in operant ethanol self-administration: the effects on immediate-early gene expression in the rat prefrontal cortex.
Echeverry-Alzate V, Tuda-Arízcun M, Bühler KM, Santos Á, Giné E, Olmos P, Gorriti MÁ, Huertas E, Rodríguez de Fonseca F, López-Moreno JA. Echeverry-Alzate V, et al. Neuropharmacology. 2012 Nov;63(6):927-35. doi: 10.1016/j.neuropharm.2012.06.010. Epub 2012 Jun 28. Neuropharmacology. 2012. PMID: 22749946
Developmentally-induced hypothyroidism alters the expression of Egr-1 and Arc genes and the sensitivity to cannabinoid agonists in the hippocampus. Possible implications for memory and learning.
Giné E, Echeverry-Alzate V, López-Moreno JA, López-Jimenez A, Torres-Romero D, Perez-Castillo A, Santos A. Giné E, et al. Mol Cell Endocrinol. 2013 Jan 5;365(1):119-28. doi: 10.1016/j.mce.2012.10.004. Epub 2012 Oct 16. Mol Cell Endocrinol. 2013. PMID: 23079472
A spontaneous deletion of α-synuclein is associated with an increase in CB1 mRNA transcript and receptor expression in the hippocampus and amygdala: effects on alcohol consumption.
López-Jiménez A, Walter NA, Giné E, Santos Á, Echeverry-Alzate V, Bühler KM, Olmos P, Giezendanner S, Moratalla R, Montoliu L, Buck KJ, López-Moreno JA. López-Jiménez A, et al. Synapse. 2013 Jun;67(6):280-9. doi: 10.1002/syn.21639. Epub 2013 Mar 20. Synapse. 2013. PMID: 23345080 Free PMC article.
31 results