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CD1d expression and invariant natural killer T-cell numbers are reduced in patients with upper gastrointestinal cancers and are further impaired by commonly used chemotherapies.
Melo AM, Conroy MJ, Foley EK, Dockry É, Breen EP, Reynolds JV, Lysaght J, Doherty DG. Melo AM, et al. Among authors: breen ep. Cancer Immunol Immunother. 2020 Jun;69(6):969-982. doi: 10.1007/s00262-020-02514-x. Epub 2020 Feb 20. Cancer Immunol Immunother. 2020. PMID: 32078695 Free PMC article.
Type 1 IFN Induction by Cytosolic Nucleic Acid Is Intact in Neonatal Mononuclear Cells, Contrasting Starkly with Neonatal Hyporesponsiveness to TLR Ligation Due to Independence from Endosome-Mediated IRF3 Activation.
Brennan K, O'Leary BD, Mc Laughlin D, Breen EP, Connolly E, Ali N, O'Driscoll DN, Ozaki E, Mahony R, Mulfaul K, Ryan AM, Ni Chianain A, McHugh A, Molloy EJ, Hogan AE, Paran S, McAuliffe FM, Doyle SL. Brennan K, et al. Among authors: breen ep. J Immunol. 2018 Aug 15;201(4):1131-1143. doi: 10.4049/jimmunol.1700956. Epub 2018 Jul 6. J Immunol. 2018. PMID: 29980613
16 results