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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 3
1997 1
1998 1
2000 1
2001 1
2002 1
2003 5
2004 1
2005 3
2006 1
2007 5
2008 4
2009 1
2010 4
2011 7
2012 13
2013 5
2014 8
2015 11
2016 15
2017 9
2018 11
2019 17
2020 12
2021 22
2022 24
2023 18
2024 10

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196 results

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Page 1
Neuropathic Pain in the Elderly.
Giovannini S, Coraci D, Brau F, Galluzzo V, Loreti C, Caliandro P, Padua L, Maccauro G, Biscotti L, Bernabei R. Giovannini S, et al. Diagnostics (Basel). 2021 Mar 30;11(4):613. doi: 10.3390/diagnostics11040613. Diagnostics (Basel). 2021. PMID: 33808121 Free PMC article. Review.
Comorbidities in Early Psoriatic Arthritis: Data From the Metabolic Disturbances in Psoriatic Arthritis Cohort Study.
Ishchenko A, Pazmino S, Neerinckx B, Lories R, de Vlam K. Ishchenko A, et al. Arthritis Care Res (Hoboken). 2024 Feb;76(2):231-240. doi: 10.1002/acr.25230. Epub 2024 Jan 15. Arthritis Care Res (Hoboken). 2024. PMID: 37667975
OBJECTIVE: The aim of this study was to investigate the prevalence of comorbidities and cardiovascular (CV) risk factors (RFs) in treatment-naive patients with early psoriatic arthritis (ePsA) and to identify factors that contribute to metabolic burden in ePsA. ...I …
OBJECTIVE: The aim of this study was to investigate the prevalence of comorbidities and cardiovascular (CV) risk factors (RFs) in treatment- …
Prediction of Chameleonic Efficiency.
David L, Wenlock M, Barton P, Ritzén A. David L, et al. ChemMedChem. 2021 Sep 6;16(17):2669-2685. doi: 10.1002/cmdc.202100306. Epub 2021 Aug 4. ChemMedChem. 2021. PMID: 34240561
A linear regression model that predicts chromatographic apparent polarity (EPSA) with a mean unsigned error of 10 A(2) was derived based on separate terms for donor, acceptor, and total molecular SASA. ...
A linear regression model that predicts chromatographic apparent polarity (EPSA) with a mean unsigned error of 10 A(2) was derived ba …
Bioisostere Effects on the EPSA of Common Permeability-Limiting Groups.
Ecker AK, Levorse DA, Victor DA, Mitcheltree MJ. Ecker AK, et al. ACS Med Chem Lett. 2022 May 23;13(6):964-971. doi: 10.1021/acsmedchemlett.2c00114. eCollection 2022 Jun 9. ACS Med Chem Lett. 2022. PMID: 35707148 Free PMC article.
Our findings reinforce EPSA's utility in optimizing permeability, highlight bioisosteres within each class that are particularly effective in lowering EPSA and others, which despite widespread use, offer little to no such benefit. Our method for matched-pair identif …
Our findings reinforce EPSA's utility in optimizing permeability, highlight bioisosteres within each class that are particularly effe …
Rapid isolation of exopolysaccharide-producing Streptococcus thermophilus based on molecular marker screening.
Xiong Z, Chen H, Song X, Xia Y, Ai L. Xiong Z, et al. J Sci Food Agric. 2022 Jan 30;102(2):862-867. doi: 10.1002/jsfa.11398. Epub 2021 Jul 6. J Sci Food Agric. 2022. PMID: 34173230
RESULTS: According to comparative analysis of EPS biosynthetic gene clusters, a conserved region of epsA (609 bp) was employed to design primer pair epsA-F/R as a molecular marker for the isolation of EPS-producing (EPS(+) ) S. thermophilus. Two EPS(+) S. thermophil …
RESULTS: According to comparative analysis of EPS biosynthetic gene clusters, a conserved region of epsA (609 bp) was employed to des …
Designing Soluble PROTACs: Strategies and Preliminary Guidelines.
García Jiménez D, Rossi Sebastiano M, Vallaro M, Mileo V, Pizzirani D, Moretti E, Ermondi G, Caron G. García Jiménez D, et al. J Med Chem. 2022 Oct 13;65(19):12639-12649. doi: 10.1021/acs.jmedchem.2c00201. Epub 2022 Apr 25. J Med Chem. 2022. PMID: 35469399 Free PMC article.
Here we measured the thermodynamic solubilities (log S) of 21 commercial PROTACs. Next, we measured BRlogD and log k(w)(IAM) (lipophilicity), EPSA, and delta log k(w)(IAM) (polarity) and showed that lipophilicity plays a major role in governing log S, but a contribution of …
Here we measured the thermodynamic solubilities (log S) of 21 commercial PROTACs. Next, we measured BRlogD and log k(w)(IAM) (lipophilicity) …
A Refinement of Clinical Tumor Marker Monitoring: Why Not Use an Inverse Value of Doubling Time?
Zaleskis G, Bosas P, Ulys A, Dabkevičiene D, Dobrovolskiene N, Hudson BA, Pašukoniene V. Zaleskis G, et al. Med Princ Pract. 2021;30(3):292-296. doi: 10.1159/000515977. Epub 2021 Mar 19. Med Princ Pract. 2021. PMID: 33744875 Free PMC article.
Conventional PSA rate of change parameters (HT and DT) were compared to a new clinically understandable ePSA parameter. RESULTS: We observed that implementation of inverse value (ePSA) rather than HT or DT has distinct advantages: (1) values are valid when PSA is un …
Conventional PSA rate of change parameters (HT and DT) were compared to a new clinically understandable ePSA parameter. RESULTS: We o …
Co-regulation of biofilm formation and antimicrobial resistance in Acinetobacter baumannii: from mechanisms to therapeutic strategies.
Mendes SG, Combo SI, Allain T, Domingues S, Buret AG, Da Silva GJ. Mendes SG, et al. Eur J Clin Microbiol Infect Dis. 2023 Dec;42(12):1405-1423. doi: 10.1007/s10096-023-04677-8. Epub 2023 Oct 28. Eur J Clin Microbiol Infect Dis. 2023. PMID: 37897520 Free PMC article. Review.
Particularly worthy of consideration are genes regulating the quorum sensing system AbaI/AbaR, AbOmpA (OmpA protein), Bap (biofilm-associated protein), the two-component regulatory system BfmRS, the PER-1 beta-lactamase, EpsA, and PTK. Finally, this review discusses ongoin …
Particularly worthy of consideration are genes regulating the quorum sensing system AbaI/AbaR, AbOmpA (OmpA protein), Bap (biofilm-associate …
EpsA is an essential gene in exopolysaccharide production in Lactobacillus johnsonii FI9785.
Dertli E, Mayer MJ, Colquhoun IJ, Narbad A. Dertli E, et al. Microb Biotechnol. 2016 Jul;9(4):496-501. doi: 10.1111/1751-7915.12314. Epub 2015 Sep 24. Microb Biotechnol. 2016. PMID: 26401596 Free PMC article.
Lactobacillus johnsonii FI9785 has an eps gene cluster which is required for the biosynthesis of homopolymeric exopolysaccharides (EPS)-1 and heteropolymeric EPS-2 as a capsular layer. The first gene of the cluster, epsA, is the putative transcriptional regulator. In this …
Lactobacillus johnsonii FI9785 has an eps gene cluster which is required for the biosynthesis of homopolymeric exopolysaccharides (EPS)-1 an …
196 results