The transient receptor potential vanilloid-3 regulates hypoxia-mediated pulmonary artery smooth muscle cells proliferation via PI3K/AKT signaling pathway.
Zhang Q, Cao Y, Luo Q, Wang P, Shi P, Song C, E M, Ren J, Fu B, Sun H.
Zhang Q, et al. Among authors: e m.
Cell Prolif. 2018 Jun;51(3):e12436. doi: 10.1111/cpr.12436. Epub 2018 Jan 22.
Cell Prolif. 2018.
PMID: 29359496
Free PMC article.
In vitro, we revealed that hypoxia promoted PASMCs viability, increased the expression of PCNA, Cyclin D, Cyclin E, Cyclin A p-CaMKII, made more cells from G(0) /G(1) phase to G(2) /M + S phase, enhanced the microtubule formation, and increased [Ca(2+) ](i) , which …
In vitro, we revealed that hypoxia promoted PASMCs viability, increased the expression of PCNA, Cyclin D, Cyclin E, Cyclin A p-CaMKII …