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Page 1
What are the DNA lesions underlying formaldehyde toxicity?
Benedict B, Kristensen SM, Duxin JP. Benedict B, et al. Among authors: duxin jp. DNA Repair (Amst). 2024 Jun;138:103667. doi: 10.1016/j.dnarep.2024.103667. Epub 2024 Mar 7. DNA Repair (Amst). 2024. PMID: 38554505 Review.
VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates.
Mirsanaye AS, Hoffmann S, Weisser M, Mund A, Lopez Mendez B, Typas D, van den Boom J, Benedict B, Hendriks IA, Nielsen ML, Meyer H, Duxin JP, Montoya G, Mailand N. Mirsanaye AS, et al. Among authors: duxin jp. Nat Commun. 2024 Mar 19;15(1):2459. doi: 10.1038/s41467-024-46760-4. Nat Commun. 2024. PMID: 38503733 Free PMC article.
The Fanconi anemia pathway repairs colibactin-induced DNA interstrand cross-links.
Altshuller M, He X, MacKrell EJ, Wernke KM, Wong JWH, Sellés-Baiget S, Wang TY, Chou TF, Duxin JP, Balskus EP, Herzon SB, Semlow DR. Altshuller M, et al. Among authors: duxin jp. bioRxiv [Preprint]. 2024 Jan 31:2024.01.30.576698. doi: 10.1101/2024.01.30.576698. bioRxiv. 2024. PMID: 38352618 Free PMC article. Preprint.
A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene.
Gao Y, Guitton-Sert L, Dessapt J, Coulombe Y, Rodrigue A, Milano L, Blondeau A, Larsen NB, Duxin JP, Hussein S, Fradet-Turcotte A, Masson JY. Gao Y, et al. Among authors: duxin jp. Nat Commun. 2023 Jan 24;14(1):381. doi: 10.1038/s41467-023-35802-y. Nat Commun. 2023. PMID: 36693839 Free PMC article.
SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway.
Schubert L, Hendriks IA, Hertz EPT, Wu W, Sellés-Baiget S, Hoffmann S, Viswalingam KS, Gallina I, Pentakota S, Benedict B, Johansen J, Apelt K, Luijsterburg MS, Rasmussen S, Lisby M, Liu Y, Nielsen ML, Mailand N, Duxin JP. Schubert L, et al. Among authors: duxin jp. EMBO Rep. 2022 Apr 5;23(4):e53639. doi: 10.15252/embr.202153639. Epub 2022 Feb 14. EMBO Rep. 2022. PMID: 35156773 Free PMC article.
A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination.
Ambjørn SM, Duxin JP, Hertz EPT, Nasa I, Duro J, Kruse T, Lopez-Mendez B, Rymarczyk B, Cressey LE, van Overeem Hansen T, Kettenbach AN, Oestergaard VH, Lisby M, Nilsson J. Ambjørn SM, et al. Among authors: duxin jp. Nat Commun. 2021 Sep 30;12(1):5748. doi: 10.1038/s41467-021-26079-0. Nat Commun. 2021. PMID: 34593815 Free PMC article.
Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway.
Liu JCY, Kühbacher U, Larsen NB, Borgermann N, Garvanska DH, Hendriks IA, Ackermann L, Haahr P, Gallina I, Guérillon C, Branigan E, Hay RT, Azuma Y, Nielsen ML, Duxin JP, Mailand N. Liu JCY, et al. Among authors: duxin jp. EMBO J. 2021 Sep 15;40(18):e107413. doi: 10.15252/embj.2020107413. Epub 2021 Aug 4. EMBO J. 2021. PMID: 34346517 Free PMC article.
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