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Switchability and minimal effect of food on pharmacokinetics of modified release tablet strengths of omecamtiv mecarbil, a cardiac myosin activator.
Trivedi A, Oberoi RK, Mackowski M, Jafarinasabian P, Zhang H, Flach S, Simiens MA, Terminello B, Abbasi S, Dutta S, Lee E. Trivedi A, et al. Among authors: dutta s. Biopharm Drug Dispos. 2021 Jul;42(7):319-328. doi: 10.1002/bdd.2293. Epub 2021 Jun 18. Biopharm Drug Dispos. 2021. PMID: 34087948 Clinical Trial.
Omecamtiv mecarbil does not prolong QTc intervals at therapeutic concentrations.
Trivedi A, Hsu CP, Jafarinasabian P, Terminello B, Zhang H, Flach S, Israel S, Brooks A, Xue H, Darpo B, Abbasi S, Dutta S, Lee E. Trivedi A, et al. Among authors: dutta s. Br J Clin Pharmacol. 2022 Jan;88(1):187-198. doi: 10.1111/bcp.14939. Epub 2021 Jul 16. Br J Clin Pharmacol. 2022. PMID: 34131942 Free article. Clinical Trial.
4,252 results