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Time-resolved FRET strategy to screen GPCR ligand library.
Oueslati N, Hounsou C, Belhocine A, Rodriguez T, Dupuis E, Zwier JM, Trinquet E, Pin JP, Durroux T. Oueslati N, et al. Among authors: durroux t. Methods Mol Biol. 2015;1272:23-36. doi: 10.1007/978-1-4939-2336-6_2. Methods Mol Biol. 2015. PMID: 25563174
Time-resolved FRET between GPCR ligands reveals oligomers in native tissues.
Albizu L, Cottet M, Kralikova M, Stoev S, Seyer R, Brabet I, Roux T, Bazin H, Bourrier E, Lamarque L, Breton C, Rives ML, Newman A, Javitch J, Trinquet E, Manning M, Pin JP, Mouillac B, Durroux T. Albizu L, et al. Among authors: durroux t. Nat Chem Biol. 2010 Aug;6(8):587-94. doi: 10.1038/nchembio.396. Epub 2010 Jul 11. Nat Chem Biol. 2010. PMID: 20622858 Free PMC article.
The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules.
Lemel L, Nieścierowicz K, García-Fernández MD, Darré L, Durroux T, Busnelli M, Pezet M, Rébeillé F, Jouhet J, Mouillac B, Domene C, Chini B, Cherezov V, Moreau CJ. Lemel L, et al. Among authors: durroux t. J Lipid Res. 2021;62:100059. doi: 10.1016/j.jlr.2021.100059. Epub 2021 Feb 26. J Lipid Res. 2021. PMID: 33647276 Free PMC article.
Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy.
Rahmeh R, Damian M, Cottet M, Orcel H, Mendre C, Durroux T, Sharma KS, Durand G, Pucci B, Trinquet E, Zwier JM, Deupi X, Bron P, Banères JL, Mouillac B, Granier S. Rahmeh R, et al. Among authors: durroux t. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6733-8. doi: 10.1073/pnas.1201093109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493271 Free PMC article.
72 results