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Identification and targeting of a unique NaV1.7 domain driving chronic pain.
Gomez K, Stratton HJ, Duran P, Loya S, Tang C, Calderon-Rivera A, François-Moutal L, Khanna M, Madura CL, Luo S, McKiver B, Choi E, Ran D, Boinon L, Perez-Miller S, Damaj MI, Moutal A, Khanna R. Gomez K, et al. Among authors: duran p. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2217800120. doi: 10.1073/pnas.2217800120. Epub 2023 Jul 27. Proc Natl Acad Sci U S A. 2023. PMID: 37498871 Free PMC article.
L5-6 Spinal Nerve Ligation-induced Neuropathy Changes the Location and Function of Ca2+ Channels and Cdk5 and Affects the Compound Action Potential in Adjacent Intact L4 Afferent Fibers.
Gomez K, Vargas-Parada A, Duran P, Sandoval A, Delgado-Lezama R, Khanna R, Felix R. Gomez K, et al. Among authors: duran p. Neuroscience. 2021 Sep 1;471:20-31. doi: 10.1016/j.neuroscience.2021.07.013. Epub 2021 Jul 22. Neuroscience. 2021. PMID: 34303780 Free PMC article.
Stereospecific Effects of Benzimidazolonepiperidine Compounds on T-Type Ca2+ Channels and Pain.
Gomez K, Tang C, Tan B, Perez-Miller S, Ran D, Loya S, Calderon-Rivera A, Stratton HJ, Duran P, Masterson KA, Gabrielsen AT, Alsbiei O, Dorame A, Serafini M, Moutal A, Wang J, Khanna R. Gomez K, et al. Among authors: duran p. ACS Chem Neurosci. 2022 Jul 6;13(13):2035-2047. doi: 10.1021/acschemneuro.2c00256. Epub 2022 Jun 7. ACS Chem Neurosci. 2022. PMID: 35671441
The natural product argentatin C attenuates postoperative pain via inhibition of voltage-gated sodium and T-type voltage-gated calcium channels.
Duran P, Loya-López S, Ran D, Tang C, Calderon-Rivera A, Gomez K, Stratton HJ, Huang S, Xu YM, Wijeratne EMK, Perez-Miller S, Shan Z, Cai S, Gabrielsen AT, Dorame A, Masterson KA, Alsbiei O, Madura CL, Luo G, Moutal A, Streicher J, Zamponi GW, Gunatilaka AAL, Khanna R. Duran P, et al. Br J Pharmacol. 2023 May;180(9):1267-1285. doi: 10.1111/bph.15974. Epub 2023 Jan 15. Br J Pharmacol. 2023. PMID: 36245395 Free article.
Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain.
Calderon-Rivera A, Gomez K, Loya-López S, Wijeratne EMK, Stratton H, Tang C, Duran P, Masterson K, Alsbiei O, Gunatilaka AAL, Khanna R. Calderon-Rivera A, et al. Among authors: duran p. Neurobiol Pain. 2023 Jan 14;13:100116. doi: 10.1016/j.ynpai.2023.100116. eCollection 2023 Jan-Jul. Neurobiol Pain. 2023. PMID: 36687466 Free PMC article.
250 results