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Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy.
Liechtenstein T, Perez-Janices N, Blanco-Luquin I, Goyvaerts C, Schwarze J, Dufait I, Lanna A, Ridder M, Guerrero-Setas D, Breckpot K, Escors D. Liechtenstein T, et al. Among authors: dufait i. Oncoimmunology. 2014 Jul 3;3(7):e945378. doi: 10.4161/21624011.2014.945378. eCollection 2014. Oncoimmunology. 2014. PMID: 25954597 Free PMC article.
Intratumoral Combinatorial Administration of CD1c (BDCA-1)+ Myeloid Dendritic Cells Plus Ipilimumab and Avelumab in Combination with Intravenous Low-Dose Nivolumab in Patients with Advanced Solid Tumors: A Phase IB Clinical Trial.
Schwarze JK, Awada G, Cras L, Tijtgat J, Forsyth R, Dufait I, Tuyaerts S, Van Riet I, Neyns B. Schwarze JK, et al. Among authors: dufait i. Vaccines (Basel). 2020 Nov 10;8(4):670. doi: 10.3390/vaccines8040670. Vaccines (Basel). 2020. PMID: 33182610 Free PMC article.
Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells.
de Mey S, Dufait I, Jiang H, Corbet C, Wang H, Van De Gucht M, Kerkhove L, Law KL, Vandenplas H, Gevaert T, Feron O, De Ridder M. de Mey S, et al. Among authors: dufait i. Int J Mol Sci. 2020 Dec 9;21(24):9367. doi: 10.3390/ijms21249367. Int J Mol Sci. 2020. PMID: 33316932 Free PMC article.
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