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In vivo optogenetic stimulation of the primate retina activates the visual cortex after long-term transduction.
Chaffiol A, Provansal M, Joffrois C, Blaize K, Labernede G, Goulet R, Burban E, Brazhnikova E, Duebel J, Pouget P, Sahel JA, Picaud S, Arcizet F, Gauvain G. Chaffiol A, et al. Among authors: duebel j. Mol Ther Methods Clin Dev. 2021 Nov 22;24:1-10. doi: 10.1016/j.omtm.2021.11.009. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2021. PMID: 34977267 Free PMC article.
Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates.
Gauvain G, Akolkar H, Chaffiol A, Arcizet F, Khoei MA, Desrosiers M, Jaillard C, Caplette R, Marre O, Bertin S, Fovet CM, Demilly J, Forster V, Brazhnikova E, Hantraye P, Pouget P, Douar A, Pruneau D, Chavas J, Sahel JA, Dalkara D, Duebel J, Benosman R, Picaud S. Gauvain G, et al. Among authors: duebel j. Commun Biol. 2021 Jan 27;4(1):125. doi: 10.1038/s42003-020-01594-w. Commun Biol. 2021. PMID: 33504896 Free PMC article.
A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina.
Chaffiol A, Caplette R, Jaillard C, Brazhnikova E, Desrosiers M, Dubus E, Duhamel L, Macé E, Marre O, Benoit P, Hantraye P, Bemelmans AP, Bamberg E, Duebel J, Sahel JA, Picaud S, Dalkara D. Chaffiol A, et al. Among authors: duebel j. Mol Ther. 2017 Nov 1;25(11):2546-2560. doi: 10.1016/j.ymthe.2017.07.011. Epub 2017 Jul 20. Mol Ther. 2017. PMID: 28807567 Free PMC article.
Noninvasive gene delivery to foveal cones for vision restoration.
Khabou H, Garita-Hernandez M, Chaffiol A, Reichman S, Jaillard C, Brazhnikova E, Bertin S, Forster V, Desrosiers M, Winckler C, Goureau O, Picaud S, Duebel J, Sahel JA, Dalkara D. Khabou H, et al. Among authors: duebel j. JCI Insight. 2018 Jan 25;3(2):e96029. doi: 10.1172/jci.insight.96029. eCollection 2018 Jan 25. JCI Insight. 2018. PMID: 29367457 Free PMC article.
Restoration of visual function by transplantation of optogenetically engineered photoreceptors.
Garita-Hernandez M, Lampič M, Chaffiol A, Guibbal L, Routet F, Santos-Ferreira T, Gasparini S, Borsch O, Gagliardi G, Reichman S, Picaud S, Sahel JA, Goureau O, Ader M, Dalkara D, Duebel J. Garita-Hernandez M, et al. Among authors: duebel j. Nat Commun. 2019 Oct 4;10(1):4524. doi: 10.1038/s41467-019-12330-2. Nat Commun. 2019. PMID: 31586094 Free PMC article.
Towards optogenetic vision restoration with high resolution.
Ferrari U, Deny S, Sengupta A, Caplette R, Trapani F, Sahel JA, Dalkara D, Picaud S, Duebel J, Marre O. Ferrari U, et al. Among authors: duebel j. PLoS Comput Biol. 2020 Jul 15;16(7):e1007857. doi: 10.1371/journal.pcbi.1007857. eCollection 2020 Jul. PLoS Comput Biol. 2020. PMID: 32667921 Free PMC article.
Generation of a Transplantable Population of Human iPSC-Derived Retinal Ganglion Cells.
Rabesandratana O, Chaffiol A, Mialot A, Slembrouck-Brec A, Joffrois C, Nanteau C, Rodrigues A, Gagliardi G, Reichman S, Sahel JA, Chédotal A, Duebel J, Goureau O, Orieux G. Rabesandratana O, et al. Among authors: duebel j. Front Cell Dev Biol. 2020 Oct 27;8:585675. doi: 10.3389/fcell.2020.585675. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33195235 Free PMC article.
29 results