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Page 1
Trial of Deferiprone in Parkinson's Disease.
Devos D, Labreuche J, Rascol O, Corvol JC, Duhamel A, Guyon Delannoy P, Poewe W, Compta Y, Pavese N, Růžička E, Dušek P, Post B, Bloem BR, Berg D, Maetzler W, Otto M, Habert MO, Lehericy S, Ferreira J, Dodel R, Tranchant C, Eusebio A, Thobois S, Marques AR, Meissner WG, Ory-Magne F, Walter U, de Bie RMA, Gago M, Vilas D, Kulisevsky J, Januario C, Coelho MVS, Behnke S, Worth P, Seppi K, Ouk T, Potey C, Leclercq C, Viard R, Kuchcinski G, Lopes R, Pruvo JP, Pigny P, Garçon G, Simonin O, Carpentier J, Rolland AS, Nyholm D, Scherfler C, Mangin JF, Chupin M, Bordet R, Dexter DT, Fradette C, Spino M, Tricta F, Ayton S, Bush AI, Devedjian JC, Duce JA, Cabantchik I, Defebvre L, Deplanque D, Moreau C; FAIRPARK-II Study Group. Devos D, et al. Among authors: duce ja. N Engl J Med. 2022 Dec 1;387(22):2045-2055. doi: 10.1056/NEJMoa2209254. N Engl J Med. 2022. PMID: 36449420 Clinical Trial.
Artificial intelligence for dementia drug discovery and trials optimization.
Doherty T, Yao Z, Khleifat AAL, Tantiangco H, Tamburin S, Albertyn C, Thakur L, Llewellyn DJ, Oxtoby NP, Lourida I; Deep Dementia Phenotyping (DEMON) Network; Ranson JM, Duce JA. Doherty T, et al. Among authors: duce ja. Alzheimers Dement. 2023 Dec;19(12):5922-5933. doi: 10.1002/alz.13428. Epub 2023 Aug 16. Alzheimers Dement. 2023. PMID: 37587767 Free article. Review.
Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function.
Carling PJ, Ryan BJ, McGuinness W, Kataria S, Humble SW, Milde S, Duce JA, Kapadia N, Zuercher WJ, Davis JB, Di Daniel E, Wade-Martins R. Carling PJ, et al. Among authors: duce ja. Autophagy. 2023 Feb;19(2):692-705. doi: 10.1080/15548627.2022.2095834. Epub 2022 Jul 25. Autophagy. 2023. PMID: 35786165 Free PMC article.
Synthesis, physicochemical characterization and neuroprotective evaluation of novel 1-hydroxypyrazin-2(1H)-one iron chelators in an in vitro cell model of Parkinson's disease.
Lewis FW, Bird K, Navarro JP, El Fallah R, Brandel J, Hubscher-Bruder V, Tsatsanis A, Duce JA, Tétard D, Bourne S, Maina M, Pienaar IS. Lewis FW, et al. Among authors: duce ja. Dalton Trans. 2022 Mar 1;51(9):3590-3603. doi: 10.1039/d1dt02604f. Dalton Trans. 2022. PMID: 35147617 Free PMC article.
The acute phase protein lactoferrin is a key feature of Alzheimer's disease and predictor of Aβ burden through induction of APP amyloidogenic processing.
Tsatsanis A, McCorkindale AN, Wong BX, Patrick E, Ryan TM, Evans RW, Bush AI, Sutherland GT, Sivaprasadarao A, Guennewig B, Duce JA. Tsatsanis A, et al. Among authors: duce ja. Mol Psychiatry. 2021 Oct;26(10):5516-5531. doi: 10.1038/s41380-021-01248-1. Epub 2021 Aug 16. Mol Psychiatry. 2021. PMID: 34400772 Free PMC article.
61 results