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The selectivity of Marinopyrrole A to induce apoptosis in MCL1high BCL2low expressing myeloma cells is related to its ability to impair protein translation.
Gomez-Bougie P, Dousset C, Descamps G, Schnitzler A, Audiger L, Tessier A, Dubreuil D, Lebreton J, Pellat-Deceunynck C, Amiot M. Gomez-Bougie P, et al. Among authors: dubreuil d. Br J Haematol. 2018 Jan;180(1):157-159. doi: 10.1111/bjh.14293. Epub 2016 Aug 14. Br J Haematol. 2018. PMID: 27523575 Free article. No abstract available.
Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity.
Kouba S, Braire J, Félix R, Chantôme A, Jaffrès PA, Lebreton J, Dubreuil D, Pipelier M, Zhang X, Trebak M, Vandier C, Mathé-Allainmat M, Potier-Cartereau M. Kouba S, et al. Among authors: dubreuil d. Eur J Med Chem. 2020 Jan 15;186:111854. doi: 10.1016/j.ejmech.2019.111854. Epub 2019 Nov 9. Eur J Med Chem. 2020. PMID: 31753515
3,4-Dideoxy-3,3,4,4-tetrafluoro- and 4-OH epimeric 3-deoxy-3,3-difluoro-α-GalCer analogues: Synthesis and biological evaluation on human iNKT cells stimulation.
Golten S, Patinec A, Akoumany K, Rocher J, Graton J, Jacquemin D, Le Questel JY, Tessier A, Lebreton J, Blot V, Pipelier M, Douillard JY, Le Pendu J, Linclau B, Dubreuil D. Golten S, et al. Among authors: dubreuil d. Eur J Med Chem. 2019 Sep 15;178:195-213. doi: 10.1016/j.ejmech.2019.05.069. Epub 2019 May 29. Eur J Med Chem. 2019. PMID: 31185411
87 results