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Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer.
Sánchez-Castillo A, Heylen E, Hounjet J, Savelkouls KG, Lieuwes NG, Biemans R, Dubois LJ, Reynders K, Rouschop KM, Vaes RDW, De Keersmaecker K, Lambrecht M, Hendriks LEL, De Ruysscher DKM, Vooijs M, Kampen KR. Sánchez-Castillo A, et al. Among authors: dubois lj. Br J Cancer. 2024 Mar;130(4):568-584. doi: 10.1038/s41416-023-02553-y. Epub 2023 Dec 30. Br J Cancer. 2024. PMID: 38160212 Free PMC article.
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, Lambin P, van der Kogel AJ, Koritzinsky M, Wouters BG. Rouschop KM, et al. J Clin Invest. 2010 Jan;120(1):127-41. doi: 10.1172/JCI40027. Epub 2009 Dec 14. J Clin Invest. 2010. PMID: 20038797 Free PMC article.
PET imaging of hypoxia using [18F]HX4: a phase I trial.
van Loon J, Janssen MH, Ollers M, Aerts HJ, Dubois L, Hochstenbag M, Dingemans AM, Lalisang R, Brans B, Windhorst B, van Dongen GA, Kolb H, Zhang J, De Ruysscher D, Lambin P. van Loon J, et al. Eur J Nucl Med Mol Imaging. 2010 Aug;37(9):1663-8. doi: 10.1007/s00259-010-1437-x. Epub 2010 Apr 6. Eur J Nucl Med Mol Imaging. 2010. PMID: 20369236 Clinical Trial.
153 results