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Exogenous Cripto-1 Suppresses Self-Renewal of Cancer Stem Cell Model.
Alam MJ, Takahashi R, Afify SM, Oo AKK, Kumon K, Nawara HM, Khayrani AC, Du J, Zahra MH, Seno A, Salomon DS, Seno M. Alam MJ, et al. Among authors: du j. Int J Mol Sci. 2018 Oct 26;19(11):3345. doi: 10.3390/ijms19113345. Int J Mol Sci. 2018. PMID: 30373174 Free PMC article.
Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment.
Oo AKK, Calle AS, Nair N, Mahmud H, Vaidyanath A, Yamauchi J, Khayrani AC, Du J, Alam MJ, Seno A, Mizutani A, Murakami H, Iwasaki Y, Chen L, Kasai T, Seno M. Oo AKK, et al. Among authors: du j. Transl Oncol. 2018 Jun;11(3):653-663. doi: 10.1016/j.tranon.2018.03.001. Epub 2018 Apr 2. Transl Oncol. 2018. PMID: 29621663 Free PMC article.
A novel model of liver cancer stem cells developed from induced pluripotent stem cells.
Afify SM, Sanchez Calle A, Hassan G, Kumon K, Nawara HM, Zahra MH, Mansour HM, Khayrani AC, Alam MJ, Du J, Seno A, Iwasaki Y, Seno M. Afify SM, et al. Among authors: du j. Br J Cancer. 2020 Apr;122(9):1378-1390. doi: 10.1038/s41416-020-0792-z. Epub 2020 Mar 17. Br J Cancer. 2020. PMID: 32203212 Free PMC article.
MEK1/2 is a bottleneck that induces cancer stem cells to activate the PI3K/AKT pathway.
Hassan G, Afify SM, Du J, Nawara HM, Sheta M, Monzur S, Zahra MH, Abu Quora HA, Mansour H, El-Ghlban S, Uesaki R, Seno A, Seno M. Hassan G, et al. Among authors: du j. Biochem Biophys Res Commun. 2021 Oct 23;583:49-55. doi: 10.1016/j.bbrc.2021.10.047. Online ahead of print. Biochem Biophys Res Commun. 2021. PMID: 34735879
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