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Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells.
Genome Biol. 2023 Apr 24;24(1):89. doi: 10.1186/s13059-023-02928-7.
Genome Biol. 2023.
PMID: 37095570
Free PMC article.
CAR NK-92 cell-mediated depletion of residual TCR+ cells for ultrapure allogeneic TCR-deleted CAR T-cell products.
Kath J, Du W, Martini S, Elsallab M, Franke C, Hartmann L, Drosdek V, Glaser V, Stein M, Schmueck-Henneresse M, Reinke P, Volk HD, Abou-El-Enein M, Wagner DL.
Kath J, et al. Among authors: drosdek v.
Blood Adv. 2023 Aug 8;7(15):4124-4134. doi: 10.1182/bloodadvances.2022009397.
Blood Adv. 2023.
PMID: 37196643
Free PMC article.
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Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, Künkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pruß A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL.
Kath J, et al. Among authors: drosdek v.
Blood. 2024 Mar 17:blood.2023020973. doi: 10.1182/blood.2023020973. Online ahead of print.
Blood. 2024.
PMID: 38493479
Free article.
Item in Clipboard
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, Künkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pruß A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL.
Kath J, et al. Among authors: drosdek v.
bioRxiv [Preprint]. 2023 Nov 14:2023.11.10.565518. doi: 10.1101/2023.11.10.565518.
bioRxiv. 2023.
PMID: 38116030
Free PMC article.
Updated.
Preprint.
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