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A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors.
Ruiz-Saenz A, Atreya CE, Wang C, Pan B, Dreyer CA, Brunen D, Prahallad A, Muñoz DP, Ramms DJ, Burghi V, Spassov DS, Fewings E, Hwang YC, Cowdrey C, Moelders C, Schwarzer C, Wolf DM, Hann B, VandenBerg SR, Shokat K, Moasser MM, Bernards R, Gutkind JS, van 't Veer LJ, Coppé JP. Ruiz-Saenz A, et al. Among authors: dreyer ca. Nat Cancer. 2023 Feb;4(2):240-256. doi: 10.1038/s43018-022-00508-5. Epub 2023 Feb 9. Nat Cancer. 2023. PMID: 36759733 Free PMC article.
Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities.
Coppé JP, Mori M, Pan B, Yau C, Wolf DM, Ruiz-Saenz A, Brunen D, Prahallad A, Cornelissen-Steijger P, Kemper K, Posch C, Wang C, Dreyer CA, Krijgsman O, Lee PRE, Chen Z, Peeper DS, Moasser MM, Bernards R, van 't Veer LJ. Coppé JP, et al. Among authors: dreyer ca. Nat Cell Biol. 2019 Jun;21(6):778-790. doi: 10.1038/s41556-019-0328-z. Epub 2019 Jun 3. Nat Cell Biol. 2019. PMID: 31160710 Free PMC article.
Two-way magnetic resonance tuning and enhanced subtraction imaging for non-invasive and quantitative biological imaging.
Wang Z, Xue X, Lu H, He Y, Lu Z, Chen Z, Yuan Y, Tang N, Dreyer CA, Quigley L, Curro N, Lam KS, Walton JH, Lin TY, Louie AY, Gilbert DA, Liu K, Ferrara KW, Li Y. Wang Z, et al. Among authors: dreyer ca. Nat Nanotechnol. 2020 Jun;15(6):482-490. doi: 10.1038/s41565-020-0678-5. Epub 2020 May 25. Nat Nanotechnol. 2020. PMID: 32451501 Free PMC article.
The Cationic Amphiphilic Drug Hexamethylene Amiloride Eradicates Bulk Breast Cancer Cells and Therapy-Resistant Subpopulations with Similar Efficiencies.
Berg AL, Rowson-Hodel A, Hu M, Keeling M, Wu H, VanderVorst K, Chen JJ, Hatakeyama J, Jilek J, Dreyer CA, Wheeler MR, Yu AM, Li Y, Carraway KL 3rd. Berg AL, et al. Among authors: dreyer ca. Cancers (Basel). 2022 Feb 14;14(4):949. doi: 10.3390/cancers14040949. Cancers (Basel). 2022. PMID: 35205696 Free PMC article.
16 results