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Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.
ChemMedChem. 2019 Aug 20;14(16):1560-1572. doi: 10.1002/cmdc.201900287. Epub 2019 Aug 5.
ChemMedChem. 2019.
PMID: 31283109
New aminoglycoside antibiotics.
Dozzo P, Moser HE.
Dozzo P, et al.
Expert Opin Ther Pat. 2010 Oct;20(10):1321-41. doi: 10.1517/13543776.2010.506189.
Expert Opin Ther Pat. 2010.
PMID: 20670208
Review.
Item in Clipboard
Synthesis and spectrum of the neoglycoside ACHN-490.
Aggen JB, Armstrong ES, Goldblum AA, Dozzo P, Linsell MS, Gliedt MJ, Hildebrandt DJ, Feeney LA, Kubo A, Matias RD, Lopez S, Gomez M, Wlasichuk KB, Diokno R, Miller GH, Moser HE.
Aggen JB, et al. Among authors: dozzo p.
Antimicrob Agents Chemother. 2010 Nov;54(11):4636-42. doi: 10.1128/AAC.00572-10. Epub 2010 Aug 30.
Antimicrob Agents Chemother. 2010.
PMID: 20805391
Free PMC article.
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Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase.
Andrews LD, Kane TR, Dozzo P, Haglund CM, Hilderbrandt DJ, Linsell MS, Machajewski T, McEnroe G, Serio AW, Wlasichuk KB, Neau DB, Pakhomova S, Waldrop GL, Sharp M, Pogliano J, Cirz RT, Cohen F.
Andrews LD, et al. Among authors: dozzo p.
J Med Chem. 2019 Aug 22;62(16):7489-7505. doi: 10.1021/acs.jmedchem.9b00625. Epub 2019 Aug 9.
J Med Chem. 2019.
PMID: 31306011
Free PMC article.
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Toward Overcoming Staphylococcus aureus Aminoglycoside Resistance Mechanisms with a Functionally Designed Neomycin Analogue.
Hanessian S, Giguère A, Grzyb J, Maianti JP, Saavedra OM, Aggen JB, Linsell MS, Goldblum AA, Hildebrandt DJ, Kane TR, Dozzo P, Gliedt MJ, Matias RD, Feeney LA, Armstrong ES.
Hanessian S, et al. Among authors: dozzo p.
ACS Med Chem Lett. 2011 Sep 29;2(12):924-8. doi: 10.1021/ml200202y. eCollection 2011 Dec 8.
ACS Med Chem Lett. 2011.
PMID: 24900282
Free PMC article.
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Toxicity modulation, resistance enzyme evasion, and A-site X-ray structure of broad-spectrum antibacterial neomycin analogs.
Maianti JP, Kanazawa H, Dozzo P, Matias RD, Feeney LA, Armstrong ES, Hildebrandt DJ, Kane TR, Gliedt MJ, Goldblum AA, Linsell MS, Aggen JB, Kondo J, Hanessian S.
Maianti JP, et al. Among authors: dozzo p.
ACS Chem Biol. 2014 Sep 19;9(9):2067-73. doi: 10.1021/cb5003416. Epub 2014 Jul 14.
ACS Chem Biol. 2014.
PMID: 25019242
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Synthesis, characterization, and plasma lipoprotein association of a nucleus-targeted boronated porphyrin.
Dozzo P, Koo MS, Berger S, Forte TM, Kahl SB.
Dozzo P, et al.
J Med Chem. 2005 Jan 27;48(2):357-9. doi: 10.1021/jm049277q.
J Med Chem. 2005.
PMID: 15658849
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Simple, high-yield methods for the synthesis of aldehydes directly from o-, m-, and p-carborane and their further conversions.
Dozzo P, Kasar RA, Kahl SB.
Dozzo P, et al.
Inorg Chem. 2005 Oct 31;44(22):8053-7. doi: 10.1021/ic0506660.
Inorg Chem. 2005.
PMID: 16241155
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