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Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy.
Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4584-9. doi: 10.1073/pnas.1402645111. Epub 2014 Mar 12.
Proc Natl Acad Sci U S A. 2014.
PMID: 24623856
Free PMC article.
A role for FKBP52 in Tau protein function.
Chambraud B, Sardin E, Giustiniani J, Dounane O, Schumacher M, Goedert M, Baulieu EE.
Chambraud B, et al. Among authors: dounane o.
Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2658-63. doi: 10.1073/pnas.0914957107. Epub 2010 Jan 25.
Proc Natl Acad Sci U S A. 2010.
PMID: 20133804
Free PMC article.
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Decrease of the immunophilin FKBP52 accumulation in human brains of Alzheimer's disease and FTDP-17.
Giustiniani J, Sineus M, Sardin E, Dounane O, Panchal M, Sazdovitch V, Duyckaerts C, Chambraud B, Baulieu EE.
Giustiniani J, et al. Among authors: dounane o.
J Alzheimers Dis. 2012;29(2):471-83. doi: 10.3233/JAD-2011-111895.
J Alzheimers Dis. 2012.
PMID: 22233767
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The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior.
Giustiniani J, Guillemeau K, Dounane O, Sardin E, Huvent I, Schmitt A, Hamdane M, Buée L, Landrieu I, Lippens G, Baulieu EE, Chambraud B.
Giustiniani J, et al. Among authors: dounane o.
FASEB J. 2015 Aug;29(8):3171-81. doi: 10.1096/fj.14-268243. Epub 2015 Apr 17.
FASEB J. 2015.
PMID: 25888602
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Caspase-cleaved Tau-D(421) is colocalized with the immunophilin FKBP52 in the autophagy-endolysosomal system of Alzheimer's disease neurons.
Meduri G, Guillemeau K, Dounane O, Sazdovitch V, Duyckaerts C, Chambraud B, Baulieu EE, Giustiniani J.
Meduri G, et al. Among authors: dounane o.
Neurobiol Aging. 2016 Oct;46:124-37. doi: 10.1016/j.neurobiolaging.2016.06.017. Epub 2016 Jul 5.
Neurobiol Aging. 2016.
PMID: 27479154
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Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress.
Chambraud B, Daguinot C, Guillemeau K, Genet M, Dounane O, Meduri G, Poüs C, Baulieu EE, Giustiniani J.
Chambraud B, et al. Among authors: dounane o.
Autophagy. 2021 Nov;17(11):3491-3510. doi: 10.1080/15548627.2021.1875611. Epub 2021 Jan 25.
Autophagy. 2021.
PMID: 33459145
Free PMC article.
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Concomitant Neuronal Tau Deposition and FKBP52 Decrease Is an Early Feature of Different Human and Experimental Tauopathies.
Meduri G, Guillemeau K, Daguinot C, Dounane O, Genet M, Ferrara L, Chambraud B, Baulieu EE, Giustiniani J.
Meduri G, et al. Among authors: dounane o.
J Alzheimers Dis. 2023;94(1):313-331. doi: 10.3233/JAD-230127.
J Alzheimers Dis. 2023.
PMID: 37248902
Free PMC article.
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