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Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders.
Huffman BM, Singh H, Ali LR, Horick N, Wang SJ, Hoffman MT, Metayer KA, Murray S, Bird A, Abrams TA, Biller LH, Chan JA, Meyerhardt JA, McCleary NJ, Goessling W, Patel AK, Wisch JS, Yurgelun MB, Mouw K, Reardon B, Van Allen EM, Zerillo JA, Clark JW, Parikh A, Mayer RJ, Schlechter B, Ng K, Kumar S, Del Vecchio Fitz C, Kuperwasser C, Hanna GJ, Coveler AL, Rubinson DA, Welsh EL, Pfaff K, Rodig S, Dougan SK, Cleary JM. Huffman BM, et al. Among authors: dougan sk. J Immunother Cancer. 2024 Jan 25;12(1):e008436. doi: 10.1136/jitc-2023-008436. J Immunother Cancer. 2024. PMID: 38272561 Free PMC article. Clinical Trial.
Localized CD47 blockade enhances immunotherapy for murine melanoma.
Ingram JR, Blomberg OS, Sockolosky JT, Ali L, Schmidt FI, Pishesha N, Espinosa C, Dougan SK, Garcia KC, Ploegh HL, Dougan M. Ingram JR, et al. Among authors: dougan sk, dougan m. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10184-10189. doi: 10.1073/pnas.1710776114. Epub 2017 Sep 5. Proc Natl Acad Sci U S A. 2017. PMID: 28874561 Free PMC article.
IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells.
Clancy-Thompson E, Ali L, Bruck PT, Exley MA, Blumberg RS, Dranoff G, Dougan M, Dougan SK. Clancy-Thompson E, et al. Among authors: dougan sk, dougan m. Cancer Immunol Res. 2018 Jan;6(1):25-35. doi: 10.1158/2326-6066.CIR-17-0490. Epub 2017 Nov 29. Cancer Immunol Res. 2018. PMID: 29187357 Free PMC article.
Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1-Specific VHHs.
Dougan M, Ingram JR, Jeong HJ, Mosaheb MM, Bruck PT, Ali L, Pishesha N, Blomberg O, Tyler PM, Servos MM, Rashidian M, Nguyen QD, von Andrian UH, Ploegh HL, Dougan SK. Dougan M, et al. Among authors: dougan sk. Cancer Immunol Res. 2018 Apr;6(4):389-401. doi: 10.1158/2326-6066.CIR-17-0495. Epub 2018 Feb 19. Cancer Immunol Res. 2018. PMID: 29459478 Free PMC article.
Inhibition of CDK4/6 Promotes CD8 T-cell Memory Formation.
Heckler M, Ali LR, Clancy-Thompson E, Qiang L, Ventre KS, Lenehan P, Roehle K, Luoma A, Boelaars K, Peters V, McCreary J, Boschert T, Wang ES, Suo S, Marangoni F, Mempel TR, Long HW, Wucherpfennig KW, Dougan M, Gray NS, Yuan GC, Goel S, Tolaney SM, Dougan SK. Heckler M, et al. Among authors: dougan sk, dougan m. Cancer Discov. 2021 Oct;11(10):2564-2581. doi: 10.1158/2159-8290.CD-20-1540. Epub 2021 May 3. Cancer Discov. 2021. PMID: 33941591 Free PMC article.
Opportunities for Utilization of DNA Repair Inhibitors in Homologous Recombination Repair-Deficient and Proficient Pancreatic Adenocarcinoma.
Cleary JM, Wolpin BM, Dougan SK, Raghavan S, Singh H, Huffman B, Sethi NS, Nowak JA, Shapiro GI, Aguirre AJ, D'Andrea AD. Cleary JM, et al. Among authors: dougan sk. Clin Cancer Res. 2021 Dec 15;27(24):6622-6637. doi: 10.1158/1078-0432.CCR-21-1367. Epub 2021 Jul 20. Clin Cancer Res. 2021. PMID: 34285063 Free PMC article. Review.
96 results