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G-CSF rescue of FOLFIRINOX-induced neutropenia leads to systemic immune suppression in mice and humans.
Cardot-Ruffino V, Bollenrucher N, Delius L, Wang SJ, Brais LK, Remland J, Keheler CE, Sullivan KM, Abrams TA, Biller LH, Enzinger PC, McCleary NJ, Patel AK, Rubinson DA, Schlechter B, Slater S, Yurgelun MB, Cleary JM, Perez K, Dougan M, Ng K, Wolpin BM, Singh H, Dougan SK. Cardot-Ruffino V, et al. Among authors: dougan sk, dougan m. J Immunother Cancer. 2023 Jun;11(6):e006589. doi: 10.1136/jitc-2022-006589. J Immunother Cancer. 2023. PMID: 37344102 Free PMC article.
IAP inhibitors enhance co-stimulation to promote tumor immunity.
Dougan M, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G. Dougan M, et al. Among authors: dougan s. J Exp Med. 2010 Sep 27;207(10):2195-206. doi: 10.1084/jem.20101123. Epub 2010 Sep 13. J Exp Med. 2010. PMID: 20837698 Free PMC article.
Clinical Dosing Regimen of Selinexor Maintains Normal Immune Homeostasis and T-cell Effector Function in Mice: Implications for Combination with Immunotherapy.
Tyler PM, Servos MM, de Vries RC, Klebanov B, Kashyap T, Sacham S, Landesman Y, Dougan M, Dougan SK. Tyler PM, et al. Among authors: dougan sk, dougan m. Mol Cancer Ther. 2017 Mar;16(3):428-439. doi: 10.1158/1535-7163.MCT-16-0496. Epub 2017 Feb 1. Mol Cancer Ther. 2017. PMID: 28148714 Free PMC article.
Targeting Immunotherapy to the Tumor Microenvironment.
Dougan M, Dougan SK. Dougan M, et al. Among authors: dougan sk. J Cell Biochem. 2017 Oct;118(10):3049-3054. doi: 10.1002/jcb.26005. Epub 2017 May 15. J Cell Biochem. 2017. PMID: 28332219 Review.
Localized CD47 blockade enhances immunotherapy for murine melanoma.
Ingram JR, Blomberg OS, Sockolosky JT, Ali L, Schmidt FI, Pishesha N, Espinosa C, Dougan SK, Garcia KC, Ploegh HL, Dougan M. Ingram JR, et al. Among authors: dougan sk, dougan m. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10184-10189. doi: 10.1073/pnas.1710776114. Epub 2017 Sep 5. Proc Natl Acad Sci U S A. 2017. PMID: 28874561 Free PMC article.
PD-L1 is an activation-independent marker of brown adipocytes.
Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL. Ingram JR, et al. Among authors: dougan sk, dougan m. Nat Commun. 2017 Sep 21;8(1):647. doi: 10.1038/s41467-017-00799-8. Nat Commun. 2017. PMID: 28935898 Free PMC article.
IAP Antagonists Enhance Cytokine Production from Mouse and Human iNKT Cells.
Clancy-Thompson E, Ali L, Bruck PT, Exley MA, Blumberg RS, Dranoff G, Dougan M, Dougan SK. Clancy-Thompson E, et al. Among authors: dougan sk, dougan m. Cancer Immunol Res. 2018 Jan;6(1):25-35. doi: 10.1158/2326-6066.CIR-17-0490. Epub 2017 Nov 29. Cancer Immunol Res. 2018. PMID: 29187357 Free PMC article.
Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1-Specific VHHs.
Dougan M, Ingram JR, Jeong HJ, Mosaheb MM, Bruck PT, Ali L, Pishesha N, Blomberg O, Tyler PM, Servos MM, Rashidian M, Nguyen QD, von Andrian UH, Ploegh HL, Dougan SK. Dougan M, et al. Among authors: dougan sk. Cancer Immunol Res. 2018 Apr;6(4):389-401. doi: 10.1158/2326-6066.CIR-17-0495. Epub 2018 Feb 19. Cancer Immunol Res. 2018. PMID: 29459478 Free PMC article.
166 results