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Genome editing in plants using the compact editor CasΦ.
Li Z, Zhong Z, Wu Z, Pausch P, Al-Shayeb B, Amerasekera J, Doudna JA, Jacobsen SE. Li Z, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2216822120. doi: 10.1073/pnas.2216822120. Epub 2023 Jan 18. Proc Natl Acad Sci U S A. 2023. PMID: 36652483 Free PMC article.
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions.
Wiedenheft B, van Duijn E, Bultema JB, Waghmare SP, Zhou K, Barendregt A, Westphal W, Heck AJ, Boekema EJ, Dickman MJ, Doudna JA. Wiedenheft B, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10092-7. doi: 10.1073/pnas.1102716108. Epub 2011 May 2. Proc Natl Acad Sci U S A. 2011. PMID: 21536913 Free PMC article.
RNA-protein analysis using a conditional CRISPR nuclease.
Lee HY, Haurwitz RE, Apffel A, Zhou K, Smart B, Wenger CD, Laderman S, Bruhn L, Doudna JA. Lee HY, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5416-21. doi: 10.1073/pnas.1302807110. Epub 2013 Mar 14. Proc Natl Acad Sci U S A. 2013. PMID: 23493562 Free PMC article.
Rational design of a split-Cas9 enzyme complex.
Wright AV, Sternberg SH, Taylor DW, Staahl BT, Bardales JA, Kornfeld JE, Doudna JA. Wright AV, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):2984-9. doi: 10.1073/pnas.1501698112. Epub 2015 Feb 23. Proc Natl Acad Sci U S A. 2015. PMID: 25713377 Free PMC article.
The structural biology of CRISPR-Cas systems.
Jiang F, Doudna JA. Jiang F, et al. Among authors: doudna ja. Curr Opin Struct Biol. 2015 Feb;30:100-111. doi: 10.1016/j.sbi.2015.02.002. Epub 2015 Feb 24. Curr Opin Struct Biol. 2015. PMID: 25723899 Free PMC article. Review.
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins.
Schumann K, Lin S, Boyer E, Simeonov DR, Subramaniam M, Gate RE, Haliburton GE, Ye CJ, Bluestone JA, Doudna JA, Marson A. Schumann K, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10437-42. doi: 10.1073/pnas.1512503112. Epub 2015 Jul 27. Proc Natl Acad Sci U S A. 2015. PMID: 26216948 Free PMC article.
Genome editing: the end of the beginning.
Doudna JA, Gersbach CA. Doudna JA, et al. Genome Biol. 2015 Dec 23;16:292. doi: 10.1186/s13059-015-0860-5. Genome Biol. 2015. PMID: 26700220 Free PMC article. No abstract available.
375 results