Doudna JA - Search Results

1

Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection.

Huang CH, Lee KC, Doudna JA. Huang CH, et al. Among authors: doudna ja. Trends Cancer. 2018 Jul;4(7):499-512. doi: 10.1016/j.trecan.2018.05.006. Epub 2018 Jun 13. Trends Cancer. 2018. PMID: 29937048 Free PMC article. Review.

2

Precise and heritable genome editing in evolutionarily diverse nematodes using TALENs and CRISPR/Cas9 to engineer insertions and deletions.

Lo TW, Pickle CS, Lin S, Ralston EJ, Gurling M, Schartner CM, Bian Q, Doudna JA, Meyer BJ. Lo TW, et al. Among authors: doudna ja. Genetics. 2013 Oct;195(2):331-48. doi: 10.1534/genetics.113.155382. Epub 2013 Aug 9. Genetics. 2013. PMID: 23934893 Free PMC article.

3

Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.

Niewoehner O, Jinek M, Doudna JA. Niewoehner O, et al. Among authors: doudna ja. Nucleic Acids Res. 2014 Jan;42(2):1341-53. doi: 10.1093/nar/gkt922. Epub 2013 Oct 22. Nucleic Acids Res. 2014. PMID: 24150936 Free PMC article.

4

Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity.

Nuñez JK, Kranzusch PJ, Noeske J, Wright AV, Davies CW, Doudna JA. Nuñez JK, et al. Among authors: doudna ja. Nat Struct Mol Biol. 2014 Jun;21(6):528-34. doi: 10.1038/nsmb.2820. Epub 2014 May 4. Nat Struct Mol Biol. 2014. PMID: 24793649 Free PMC article.

5

Programmable RNA recognition and cleavage by CRISPR/Cas9.

O'Connell MR, Oakes BL, Sternberg SH, East-Seletsky A, Kaplan M, Doudna JA. O'Connell MR, et al. Among authors: doudna ja. Nature. 2014 Dec 11;516(7530):263-6. doi: 10.1038/nature13769. Epub 2014 Sep 28. Nature. 2014. PMID: 25274302 Free PMC article.

6

Cutting it close: CRISPR-associated endoribonuclease structure and function.

Hochstrasser ML, Doudna JA. Hochstrasser ML, et al. Among authors: doudna ja. Trends Biochem Sci. 2015 Jan;40(1):58-66. doi: 10.1016/j.tibs.2014.10.007. Epub 2014 Nov 18. Trends Biochem Sci. 2015. PMID: 25468820 Review.

7

Integrase-mediated spacer acquisition during CRISPR-Cas adaptive immunity.

Nuñez JK, Lee AS, Engelman A, Doudna JA. Nuñez JK, et al. Among authors: doudna ja. Nature. 2015 Mar 12;519(7542):193-8. doi: 10.1038/nature14237. Epub 2015 Feb 18. Nature. 2015. PMID: 25707795 Free PMC article.

8

The structural biology of CRISPR-Cas systems.

Jiang F, Doudna JA. Jiang F, et al. Among authors: doudna ja. Curr Opin Struct Biol. 2015 Feb;30:100-111. doi: 10.1016/j.sbi.2015.02.002. Epub 2015 Feb 24. Curr Opin Struct Biol. 2015. PMID: 25723899 Free PMC article. Review.

9

Expanding the Biologist's Toolkit with CRISPR-Cas9.

Sternberg SH, Doudna JA. Sternberg SH, et al. Among authors: doudna ja. Mol Cell. 2015 May 21;58(4):568-74. doi: 10.1016/j.molcel.2015.02.032. Mol Cell. 2015. PMID: 26000842 Free article. Review.

10

Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

Redding S, Sternberg SH, Marshall M, Gibb B, Bhat P, Guegler CK, Wiedenheft B, Doudna JA, Greene EC. Redding S, et al. Among authors: doudna ja. Cell. 2015 Nov 5;163(4):854-65. doi: 10.1016/j.cell.2015.10.003. Cell. 2015. PMID: 26522594 Free PMC article.

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