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CRL2ZER1/ZYG11B recognizes small N-terminal residues for degradation.
Li Y, Zhao Y, Yan X, Ye C, Weirich S, Zhang B, Wang X, Song L, Jiang C, Jeltsch A, Dong C, Mi W. Li Y, et al. Among authors: dong c. Nat Commun. 2022 Dec 10;13(1):7636. doi: 10.1038/s41467-022-35169-6. Nat Commun. 2022. PMID: 36496439 Free PMC article.
Recognition of nonproline N-terminal residues by the Pro/N-degron pathway.
Dong C, Chen SJ, Melnykov A, Weirich S, Sun K, Jeltsch A, Varshavsky A, Min J. Dong C, et al. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14158-14167. doi: 10.1073/pnas.2007085117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513738 Free PMC article.
Structure of AcrVIA2 and its binding mechanism to CRISPR-Cas13a.
Song G, Li X, Wang Z, Dong C, Xie X, Yan X. Song G, et al. Among authors: dong c. Biochem Biophys Res Commun. 2022 Jul 5;612:84-90. doi: 10.1016/j.bbrc.2022.04.091. Epub 2022 Apr 23. Biochem Biophys Res Commun. 2022. PMID: 35512461
Structural insights into ORF10 recognition by ZYG11B.
Zhang B, Li Y, Feng Q, Song L, Dong C, Yan X. Zhang B, et al. Among authors: dong c. Biochem Biophys Res Commun. 2022 Aug 6;616:14-18. doi: 10.1016/j.bbrc.2022.05.069. Epub 2022 May 20. Biochem Biophys Res Commun. 2022. PMID: 35636250 Free PMC article.
C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Ru Y, Yan X, Zhang B, Song L, Feng Q, Ye C, Zhou Z, Yang Z, Li Y, Zhang Z, Li Q, Mi W, Dong C. Ru Y, et al. Among authors: dong c. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2203218119. doi: 10.1073/pnas.2203218119. Epub 2022 Jul 22. Proc Natl Acad Sci U S A. 2022. PMID: 35867826 Free PMC article.
Recognition of an Ala-rich C-degron by the E3 ligase Pirh2.
Wang X, Li Y, Yan X, Yang Q, Zhang B, Zhang Y, Yuan X, Jiang C, Chen D, Liu Q, Liu T, Mi W, Yu Y, Dong C. Wang X, et al. Among authors: dong c. Nat Commun. 2023 Apr 29;14(1):2474. doi: 10.1038/s41467-023-38173-6. Nat Commun. 2023. PMID: 37120596 Free PMC article.
6,947 results