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Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.
Shu S, Lin CY, He HH, Witwicki RM, Tabassum DP, Roberts JM, Janiszewska M, Huh SJ, Liang Y, Ryan J, Doherty E, Mohammed H, Guo H, Stover DG, Ekram MB, Brown J, D'Santos C, Krop IE, Dillon D, McKeown M, Ott C, Qi J, Ni M, Rao PK, Duarte M, Wu SY, Chiang CM, Anders L, Young RA, Winer E, Letai A, Barry WT, Carroll JS, Long H, Brown M, Liu XS, Meyer CA, Bradner JE, Polyak K. Shu S, et al. Among authors: doherty e. Nature. 2016 Jan 21;529(7586):413-417. doi: 10.1038/nature16508. Epub 2016 Jan 6. Nature. 2016. PMID: 26735014 Free PMC article.
A universal mode of helix packing in RNA.
Doherty EA, Batey RT, Masquida B, Doudna JA. Doherty EA, et al. Nat Struct Biol. 2001 Apr;8(4):339-43. doi: 10.1038/86221. Nat Struct Biol. 2001. PMID: 11276255
Emerging themes in RNA folding.
Doudna JA, Doherty EA. Doudna JA, et al. Among authors: doherty ea. Fold Des. 1997;2(5):R65-70. doi: 10.1016/S1359-0278(97)00035-7. Fold Des. 1997. PMID: 9377708 Review.
Ribozyme structures and mechanisms.
Doherty EA, Doudna JA. Doherty EA, et al. Annu Rev Biochem. 2000;69:597-615. doi: 10.1146/annurev.biochem.69.1.597. Annu Rev Biochem. 2000. PMID: 10966470 Review.
Ribozyme structures and mechanisms.
Doherty EA, Doudna JA. Doherty EA, et al. Annu Rev Biophys Biomol Struct. 2001;30:457-75. doi: 10.1146/annurev.biophys.30.1.457. Annu Rev Biophys Biomol Struct. 2001. PMID: 11441810 Review.
The P5abc peripheral element facilitates preorganization of the tetrahymena group I ribozyme for catalysis.
Engelhardt MA, Doherty EA, Knitt DS, Doudna JA, Herschlag D. Engelhardt MA, et al. Among authors: doherty ea. Biochemistry. 2000 Mar 14;39(10):2639-51. doi: 10.1021/bi992313g. Biochemistry. 2000. PMID: 10704214
Structural comparisons using solution-based free radical cleavage revealed that a ribozyme lacking P5abc (E(DeltaP5abc)) and E(DeltaP5abc) with P5abc added in trans (E(DeltaP5abc).P5abc) adopt a similar global tertiary structure at Mg(2+) concentrations great …
Structural comparisons using solution-based free radical cleavage revealed that a ribozyme lacking P5abc (E(DeltaP5abc)) and E …
[No title available]
[No authors listed] [No authors listed] PMID: 34700397
374 results